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ULK1 knockout suppresses pancreatic cancer progression by inhibiting autophagy and enhancing antitumor immunity

Hana Jeong
Jinju Lee
Heesun Cheong
ResearchOpen Access17 Dec 2025
Experimental & Molecular Medicine

Volume: 57, P: 2816-2832
The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism

Ferroptosis is an iron-dependent cell death mechanism that is emerging as a target for cancer therapy. Here, the authors find that lipoprotein-associated phospholipase A2 modulates ferroptosis resistance by controlling phospholipid metabolism.

Mihee Oh
Seo Young Jang
Eun-Woo Lee
ResearchOpen Access15 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Haplotype-resolved genome assembly and resequencing analysis provide insights into genome evolution and allelic imbalance in Pinus densiflora

Chromosome-scale and haplotype-resolved assembly of Pinus densiflora sheds light on Pinus-specific genome enlargement. Comparison between haplotypes and resequencing of 30 wild accessions show allelic imbalance with roles in flowering regulation and stress resistance.

Min-Jeong Jang
Hye Jeong Cho
Seungill Kim
Research20 Oct 2024
Nature Genetics

Volume: 56, P: 2551-2561
PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase

Yangsoon Lee
Su Jin Kim
Sang Seok Koh
ResearchOpen Access05 Apr 2011
Experimental & Molecular Medicine

Volume: 43, P: 291-297
NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function

Ji-Hee Kim
Ji-Yoon Kim
Young-Myeong Kim
ResearchOpen Access07 Aug 2020
Experimental & Molecular Medicine

Volume: 52, P: 1298-1309
Association between intraoperative tidal volume and postoperative acute kidney injury in non-cardiac surgical patients using a propensity score-weighted analysis

Ji-Yoon Jung
Seung Eun Song
Hyun-Kyu Yoon
ResearchOpen Access29 Aug 2024
Scientific Reports

Volume: 14, P: 1-9
Loss-of-function gs3 allele decreases methane emissions and increases grain yield in rice

Rice paddies are a source of the potent greenhouse gas methane. The authors demonstrate that a rice variety containing naturally lost function in the gene GS3 has reduced allocation of photosynthates to roots, which results in a reduction of methane emissions during growth.

Youngho Kwon
Ji-Yoon Lee
Choong-Min Ryu
ResearchOpen Access27 Nov 2023
Nature Climate Change

Volume: 13, P: 1329-1333
c-MET as a Potential Therapeutic Target in Ovarian Clear Cell Carcinoma

Ha-Jeong Kim
Aera Yoon
Duk-Soo Bae
ResearchOpen Access05 Dec 2016
Scientific Reports

Volume: 6, P: 1-9
A new way to create ether lipids

A crucial step in the cell-death process of ferroptosis is the incorporation of free polyunsaturated fatty acids (PUFAs) into membrane phospholipids. An enzyme has now been identified that contributes to ferroptosis by directly transferring PUFAs from phospholipids to ether lysophospholipids to form ether phospholipids.

Ji-Yoon Lee
Jong Woo Kim
Eun-Woo Lee
News & Views13 Feb 2023
Nature Chemical Biology

Volume: 19, P: 259-260
Publisher Correction: Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion

Suji Kim
Sungbo Shim
Young-Myeong Kim
Amendments and CorrectionsOpen Access18 Jul 2024
Experimental & Molecular Medicine

Volume: 56, P: 1682
(Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia

Ji Yoon Lee
Hee-Je Kim
ReviewsOpen Access21 Nov 2014
Experimental & Molecular Medicine

Volume: 46, P: e122
Neurophysiological correlates of altered response inhibition in internet gaming disorder and obsessive-compulsive disorder: Perspectives from impulsivity and compulsivity

Minah Kim
Tak Hyung Lee
Jun Soo Kwon
ResearchOpen Access30 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
Anti-Tumor Effects of Wee1 Kinase Inhibitor with Radiotherapy in Human Cervical Cancer

Yoo-Young Lee
Young-Jae Cho
Jeong-Won Lee
ResearchOpen Access28 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner

Jong Woo Kim
Min-Ju Kim
Eun-Woo Lee
ResearchOpen Access26 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-11
Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease

Hye Yun Kim
Hyunjin V. Kim
YoungSoo Kim
ResearchOpen Access12 Dec 2014
Scientific Reports

Volume: 4, P: 1-7
Dexras1 links glucocorticoids to insulin-like growth factor-1 signaling in adipogenesis

Hyo Jung Kim
Jiyoung Y. Cha
Jae-woo Kim
ResearchOpen Access27 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
The anti-cancer effects of itraconazole in epithelial ovarian cancer

Chel Hun Choi
Ji-Yoon Ryu
Jeong-Won Lee
ResearchOpen Access26 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Generation of pure lymphatic endothelial cells from human pluripotent stem cells and their therapeutic effects on wound repair

Shin-Jeong Lee
Changwon Park
Young-sup Yoon
ResearchOpen Access12 Jun 2015
Scientific Reports

Volume: 5, P: 1-13
Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Tae-Jun Park
Jei Hyoung Park
Sang Chul Lee
ResearchOpen Access04 Nov 2019
Cell Death & Disease

Volume: 10, P: 1-15
Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion

Suji Kim
Sungbo Shim
Young-Myeong Kim
ResearchOpen Access03 Jun 2024
Experimental & Molecular Medicine

Volume: 56, P: 1388-1400
Chloroquine reverses chemoresistance via upregulation of p21^WAF1/CIP1 and autophagy inhibition in ovarian cancer

Jae Ryoung Hwang
Woo Young Kim
Jeong-Won Lee
ResearchOpen Access04 Dec 2020
Cell Death & Disease

Volume: 11, P: 1-17
Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer

Yi Yang
Woo Kyun Bae
Hangun Kim
ResearchOpen Access02 Nov 2018
Scientific Reports

Volume: 8, P: 1-11
Nogo-A regulates myogenesis via interacting with Filamin-C

SunYoung Park
Ji-Hwan Park
Kyu-Shik Jeong
ResearchOpen Access06 Jan 2021
Cell Death Discovery

Volume: 7, P: 1-18
Pulmonary artery catheter monitoring versus arterial waveform-based monitoring during liver transplantation: a retrospective cohort study

Ji-Yoon Jung
Jin Young Sohn
Won Ho Kim
ResearchOpen Access15 Nov 2023
Scientific Reports

Volume: 13, P: 1-11
Serum neutrophil gelatinase-associated lipocalin and lactate level during surgery predict acute kidney injury and early allograft dysfunction after liver transplantation

Hyeyeon Cho
Ji-Yoon Jung
Kyung-Suk Suh
ResearchOpen Access27 May 2023
Scientific Reports

Volume: 13, P: 1-10
Transverse abdominis plane block compared with patient-controlled epidural analgesia following abdominal surgery: a meta-analysis and trial sequential analysis

Young Hyun Jeong
Ji-Yoon Jung
Won Ho Kim
ResearchOpen Access29 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
Inoculation effect of Pseudomonas sp. TF716 on N₂O emissions during rhizoremediation of diesel-contaminated soil

Ji-Yoon Kim
Kyung-Suk Cho
ResearchOpen Access29 Jul 2022
Scientific Reports

Volume: 12, P: 1-12
EEG Dataset for the Recognition of Different Emotions Induced in Voice-User Interaction

Ga-Young Choi
Jong-Gyu Shin
Han-Jeong Hwang
ResearchOpen Access03 Oct 2024
Scientific Data

Volume: 11, P: 1-12
The stress-responsive protein REDD1 and its pathophysiological functions

Ji-Yoon Kim
Young-Guen Kwon
Young-Myeong Kim
ReviewsOpen Access01 Sept 2023
Experimental & Molecular Medicine

Volume: 55, P: 1933-1944
An integrated view of lipid metabolism in ferroptosis revisited via lipidomic analysis

Jong Woo Kim
Ji-Yoon Lee
Eun-Woo Lee
ReviewsOpen Access23 Aug 2023
Experimental & Molecular Medicine

Volume: 55, P: 1620-1631

Search

ULK1 knockout suppresses pancreatic cancer progression by inhibiting autophagy and enhancing antitumor immunity

The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism

Haplotype-resolved genome assembly and resequencing analysis provide insights into genome evolution and allelic imbalance in Pinus densiflora

PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase

NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function

Association between intraoperative tidal volume and postoperative acute kidney injury in non-cardiac surgical patients using a propensity score-weighted analysis

Loss-of-function gs3 allele decreases methane emissions and increases grain yield in rice

c-MET as a Potential Therapeutic Target in Ovarian Clear Cell Carcinoma

A new way to create ether lipids

Publisher Correction: Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion

(Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia

Neurophysiological correlates of altered response inhibition in internet gaming disorder and obsessive-compulsive disorder: Perspectives from impulsivity and compulsivity

Anti-Tumor Effects of Wee1 Kinase Inhibitor with Radiotherapy in Human Cervical Cancer

FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner

Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease

Dexras1 links glucocorticoids to insulin-like growth factor-1 signaling in adipogenesis

The anti-cancer effects of itraconazole in epithelial ovarian cancer

Generation of pure lymphatic endothelial cells from human pluripotent stem cells and their therapeutic effects on wound repair

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion

Chloroquine reverses chemoresistance via upregulation of p21^WAF1/CIP1 and autophagy inhibition in ovarian cancer

Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer

Nogo-A regulates myogenesis via interacting with Filamin-C

Pulmonary artery catheter monitoring versus arterial waveform-based monitoring during liver transplantation: a retrospective cohort study

Serum neutrophil gelatinase-associated lipocalin and lactate level during surgery predict acute kidney injury and early allograft dysfunction after liver transplantation

Transverse abdominis plane block compared with patient-controlled epidural analgesia following abdominal surgery: a meta-analysis and trial sequential analysis

Inoculation effect of Pseudomonas sp. TF716 on N₂O emissions during rhizoremediation of diesel-contaminated soil

EEG Dataset for the Recognition of Different Emotions Induced in Voice-User Interaction

The stress-responsive protein REDD1 and its pathophysiological functions

An integrated view of lipid metabolism in ferroptosis revisited via lipidomic analysis

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