Nature Search

Assisting scalable diagnosis automatically via CT images in the combat against COVID-19

Bohan Liu
Pan Liu
Kunlun He
ResearchOpen Access18 Feb 2021
Scientific Reports

Volume: 11, P: 1-8
Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in trauma-induced coagulopathy

Qingsong Chen
Tao Li
Dingyuan Du
ResearchOpen Access08 Jul 2025
Scientific Reports

Volume: 15, P: 1-21
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins

Here, Ning et al report the cellular interactomes of Crimean-Congo haemorrhagic fever virus glycoproteins and uncover a host restriction factor HAX1 that hijacks the viral glycoproteins to mitochondria, disabling progeny virion packaging.

Shiyu Dai
Yuan-Qin Min
Yun-Jia Ning
ResearchOpen Access14 Nov 2023
Nature Communications

Volume: 14, P: 1-18
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir

In this study, the authors report the structure-based discovery and preclinical evaluation of 2 simnotrelvir, an orally bioavailable 3CLpro inhibitor that blocks replication of SARS-CoV-2 variants in 3 vitro, shows robust efficacy in a mouse model and good safety and pharmacokinetic profiles in rats 4 and monkeys.

Xiangrui Jiang
Haixia Su
Yechun Xu
ResearchOpen Access13 Oct 2023
Nature Communications

Volume: 14, P: 1-15
s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand–foot skin reaction that can be reversed by nicotinamide

Peihua Luo
Hao Yan
Qiaojun He
ResearchOpen Access15 Apr 2020
Cell Research

Volume: 30, P: 779-793
Distinct multilevel misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy

Xing Sun
Yongjia Duan
Yanshan Fang
ResearchOpen Access20 Sept 2018
Cell Death & Disease

Volume: 9, P: 1-16
Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2

Xin Pan
Fang Ye
Yang Du
ResearchOpen Access28 Nov 2023
Cell Discovery

Volume: 9, P: 1-17
SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses

Shufen Li
Yulan Zhang
Ke Peng
Research17 Jan 2023
Cell Research

Volume: 33, P: 201-214
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir

Yumin Zhang
Yuan Sun
Leike Zhang
ResearchOpen Access22 Sept 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-10
A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles

Ya-Nan Zhang
Xiao-Dan Li
Bo Zhang
CorrespondenceOpen Access25 Aug 2020
Cell Research

Volume: 30, P: 1046-1048

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