Nature Search

Sandwiching of MOF nanoparticles between graphene oxide nanosheets among ice grains

Conventional methods for nanoparticle cluster formation involve surface functionalization, which can alter the properties. Here, the authors propose a non-disruptive strategy to position nanomaterials of different shapes between nanosheets without the need for pre-modification.

Youhua Lu
Ye-Guang Fang
Jianjun Wang
ResearchOpen Access10 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Comparative genetic architectures of schizophrenia in East Asian and European populations

Genome-wide meta-analysis with individuals of East Asian or European ancestry identifies 176 loci associated with schizophrenia. Despite consistent genetic effects across populations, polygenic risk models trained in one population have reduced performance in the other population.

Max Lam
Chia-Yen Chen
Hailiang Huang
Research18 Nov 2019
Nature Genetics

Volume: 51, P: 1670-1678
Erratum: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

Min Deng
Ling Wei
Xuejun Zhang
Amendments and Corrections29 May 2013
Nature Genetics

Volume: 45, P: 714
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Dynamic urea bond for the design of reversible and self-healing polymers

The design of dynamic covalent bonds is crucial to self-healing polymer materials, but the reaction normally occurs in the presence of heat or/and catalysts. Ying et al.report a catalyst-free design of dynamic urea bonds that are capable of autonomous repairing at low temperature.

Hanze Ying
Yanfeng Zhang
Jianjun Cheng
Research04 Feb 2014
Nature Communications

Volume: 5, P: 1-9
Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Small cell lung cancer (SCLC) may evolve under treatment. But tumor tissues are often not available to study evolution of SCLC. Here, the authors utilize circulating tumor DNA to investigate the genomic evolution and subclonal architecture of SCLC during therapy.

Jingying Nong
Yuhua Gong
Jinghui Wang
ResearchOpen Access06 Aug 2018
Nature Communications

Volume: 9, P: 1-8
Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

In a randomized phase 3 trial, neoadjuvant anti-PD-1 plus either paclitaxel and cisplatin or nab-paclitaxel and cisplatin elicited a significantly superior pathological complete response rate versus neoadjuvant paclitaxel and cisplatin alone in patients with resectable locally advanced esophageal squamous cell carcinoma.

Jianjun Qin
Liyan Xue
Yin Li
ResearchOpen Access02 Jul 2024
Nature Medicine

Volume: 30, P: 2549-2557
Publisher Correction: Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang
Hengyou Weng
Jianjun Chen
Amendments and Corrections27 Aug 2020
Nature Cell Biology

Volume: 22, P: 1288
Author Correction: Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang
Hengyou Weng
Jianjun Chen
Amendments and Corrections07 Jun 2018
Nature Cell Biology

Volume: 20, P: 1098
New loci and coding variants confer risk for age-related macular degeneration in East Asians

Age-related macular degeneration (AMD) is a major cause of blindness worldwide. Here, the authors carry out a two-stage genome-wide association study for AMD and identify three new AMD risk loci, highlighting the shared and distinct genetic basis of the disease in East Asians and Europeans.

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
ResearchOpen Access28 Jan 2015
Nature Communications

Volume: 6, P: 1-10
Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Jingying Nong
Yuhua Gong
Jinghui Wang
Amendments and CorrectionsOpen Access29 Jan 2019
Nature Communications

Volume: 10, P: 1
Effects of dietary Brassica rapa L. polysaccharide on growth performance, immune and antioxidant functions and intestinal flora of yellow-feathered quail

Jianjun Zhu
Zhengli Wang
Hong Shen
ResearchOpen Access16 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

Min Deng, Kai Wang and colleagues report genome-wide association analyses of amyotrophic lateral sclerosis in the Han Chinese population. They identify two new risk loci at 1q32 and 22p11.

Min Deng
Ling Wei
Xuejun Zhang
Research28 Apr 2013
Nature Genetics

Volume: 45, P: 697-700
High myosin binding protein H expression predicts poor prognosis in glioma patients

Jianfei Zhang
Qianqiao Guo
Yujin Yan
ResearchOpen Access27 Jan 2022
Scientific Reports

Volume: 12, P: 1-10
Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

Jian Yang
Yuhua Gong
Peiwu Yu
ResearchOpen Access11 May 2020
Cell Death & Disease

Volume: 11, P: 1-9
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy

Combination therapy with α-CTLA-4 and α-PD-1 is showing improved therapeutic effects in clinical trials. Here, the authors report that mechanistically in bladder cancer such effect depends upon an upregulation of T cell activity mediated by the IL-7/IL-7R and IFN-γ/IFN-γR signalling pathways.

Lewis Zhichang Shi
Tihui Fu
Padmanee Sharma
ResearchOpen Access08 Aug 2016
Nature Communications

Volume: 7, P: 1-12
Correction: Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
Amendments and Corrections30 Mar 2015
Nature Communications

Volume: 6, P: 1
Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huang et al. identify IGF2BPs as an additional class of N⁶-methyladenosine (m⁶A) reader proteins. They find that IGF2BPs selectively bind to m⁶A-containing mRNAs and promote their stability.

Huilin Huang
Hengyou Weng
Jianjun Chen
Research23 Feb 2018
Nature Cell Biology

Volume: 20, P: 285-295
VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

Prostate cancer is refractory to anti-CTLA-4 therapy, but the reason why is unclear. Padmanee Sharma and colleagues report that the inhibitory molecule VISTA, which negatively regulates T cells, is upregulated on macrophages in prostate tumors that have been treated with anti-CTLA-4 and may play a role in resistance to this immunotherapy.

Jianjun Gao
John F Ward
Padmanee Sharma
Research27 Mar 2017
Nature Medicine

Volume: 23, P: 551-555
Probing the critical nucleus size for ice formation with graphene oxide nanosheets

Nucleation experiments with water droplets containing differently sized graphene oxide nanosheets provide an experimental indication of the temperature-dependent size of the critical ice nucleus.

Guoying Bai
Dong Gao
Jianjun Wang
Research18 Dec 2019
Nature

Volume: 576, P: 437-441
Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia

Ten-eleven translocation 1 (TET1) is a critical oncoprotein in AML. Here, the authors identify 2 compounds that target the binding of STAT3/5 specifically to the TET1 promoter, inhibiting its expression and AML cell viability.

Xi Jiang
Chao Hu
Jianjun Chen
ResearchOpen Access13 Dec 2017
Nature Communications

Volume: 8, P: 1-13
Histone H3 trimethylation at lysine 36 guides m⁶A RNA modification co-transcriptionally

METTL14 recognizes the trimethyl mark on lysine 36 of histone H3 that directs m⁶A modifications co-transcriptionally.

Huilin Huang
Hengyou Weng
Jianjun Chen
Research13 Mar 2019
Nature

Volume: 567, P: 414-419
An Injectable Oxygen Release System to Augment Cell Survival and Promote Cardiac Repair Following Myocardial Infarction

Zhaobo Fan
Zhaobin Xu
Jianjun Guan
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-22
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Qing Lan and colleagues report the results of a genome-wide association study of lung cancer in never-smoking women from Asia. They identify three new susceptibility loci and confirm three other previously reported associations.

Qing Lan
Chao A Hsiung
Nathaniel Rothman
Research11 Nov 2012
Nature Genetics

Volume: 44, P: 1330-1335
Thermosensitive and antioxidant wound dressings capable of adaptively regulating TGFβ pathways promote diabetic wound healing

Hong Niu
Ya Guan
Jianjun Guan
ResearchOpen Access08 Jul 2023
npj Regenerative Medicine

Volume: 8, P: 1-19
Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene

A multi-omic analysis of 11 Mycobacterium tuberculosis (Mtb) isolates with different drug resistance profiles leads to the discovery of Rv3094c, an enzyme capable of activating the clinically relevant Mtb drug, ethionamide.

Li Wan
Peilei Hu
Hongtai Zhang
ResearchOpen Access07 Feb 2023
Communications Biology

Volume: 6, P: 1-14
Large-scale photovoltaic solar farms in the Sahara affect solar power generation potential globally

Large solar farms in the Sahara Desert could redistribute solar power generation potential locally as well as globally through disturbance of large-scale atmospheric teleconnections, according to simulations with an Earth system model.

Jingchao Long
Zhengyao Lu
Qiong Zhang
ResearchOpen Access08 Jan 2024
Communications Earth & Environment

Volume: 5, P: 1-9
Targeting angiogenesis for fracture nonunion treatment in inflammatory disease

Cuicui Wang
Jun Ying
Jie Shen
ResearchOpen Access07 Jun 2021
Bone Research

Volume: 9, P: 1-13
Safety measures for COVID-19 do not compromise the outcomes of patients undergoing primary percutaneous coronary intervention: a single center retrospective study

Xiaonan Guan
Jianjun Zhang
Ning Ma
ResearchOpen Access11 May 2021
Scientific Reports

Volume: 11, P: 1-9
Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma

Xuewen Liu
Fang Wang
Likun Chen
Research03 Dec 2020
Oncogene

Volume: 40, P: 821-832
Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated MLH1 and wild-type BRAF and KRAS

Jing Wang
Yuting Yi
Zhiyong Liang
Research05 Feb 2019
Modern Pathology

Volume: 32, P: 1053-1064
Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling

Yan Song
Jian Gao
KeWei Wang
ResearchOpen Access13 Jun 2018
Cell Death & Disease

Volume: 9, P: 1-14
Neural tube defects: role of lithium carbonate exposure in embryonic neural development in a murine model

Shen Li
Danqing Luo
Jianhua Wang
Research10 Nov 2020
Pediatric Research

Volume: 90, P: 82-92
Exome sequencing identifies a novel CEACAM16 mutation associated with autosomal dominant nonsyndromic hearing loss DFNA4B in a Chinese family

Honghan Wang
Xinwei Wang
Yong Feng
Research15 Jan 2015
Journal of Human Genetics

Volume: 60, P: 119-126

Search

Sandwiching of MOF nanoparticles between graphene oxide nanosheets among ice grains

Comparative genetic architectures of schizophrenia in East Asian and European populations

Erratum: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Dynamic urea bond for the design of reversible and self-healing polymers

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Publisher Correction: Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Author Correction: Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

New loci and coding variants confer risk for age-related macular degeneration in East Asians

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

Effects of dietary Brassica rapa L. polysaccharide on growth performance, immune and antioxidant functions and intestinal flora of yellow-feathered quail

Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

High myosin binding protein H expression predicts poor prognosis in glioma patients

Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy

Correction: Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

Recognition of RNA N⁶-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

Probing the critical nucleus size for ice formation with graphene oxide nanosheets

Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia

Histone H3 trimethylation at lysine 36 guides m⁶A RNA modification co-transcriptionally

An Injectable Oxygen Release System to Augment Cell Survival and Promote Cardiac Repair Following Myocardial Infarction

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Thermosensitive and antioxidant wound dressings capable of adaptively regulating TGFβ pathways promote diabetic wound healing

Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene

Large-scale photovoltaic solar farms in the Sahara affect solar power generation potential globally

Targeting angiogenesis for fracture nonunion treatment in inflammatory disease

Safety measures for COVID-19 do not compromise the outcomes of patients undergoing primary percutaneous coronary intervention: a single center retrospective study

Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma

Prevalence of recurrent oncogenic fusion in mismatch repair-deficient colorectal carcinoma with hypermethylated MLH1 and wild-type BRAF and KRAS

Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling

Neural tube defects: role of lithium carbonate exposure in embryonic neural development in a murine model

Exome sequencing identifies a novel CEACAM16 mutation associated with autosomal dominant nonsyndromic hearing loss DFNA4B in a Chinese family

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