Nature Search

Slipknot-gauged mechanical transmission and robotic operation

A mechano-intelligent transmission mechanism based on the slipknot delivers precise force signals for clinical practice and robotic operations such as minimally invasive surgery and tendon-driven robotics.

Yaoting Xue
Jiasheng Cao
Xiujun Cai
ResearchOpen Access26 Nov 2025
Nature

Volume: 647, P: 889-896
Allogeneic CD19-targeting T cells for treatment-refractory systemic lupus erythematosus: a phase 1 trial

In a small trial of patients with severe systemic lupus erythematosus and nephritis, treatment with allogeneic T cells with a CD19 chimeric antigen receptor inserted into the T cell receptor locus and deletion of the PD-1 (PDCD1) gene were safe and associated with reduced disease activity.

Xiaobing Wang
Yi Zhang
Huji Xu
Research27 Aug 2025
Nature Medicine

Volume: 31, P: 3713-3724
Rhodium-catalysed direct hydroarylation of alkenes and alkynes with phosphines through phosphorous-assisted C−H activation

Dialkyl biaryl phosphines find wide application in catalysis as ligands. Here, the authors report a rhodium-catalysed hydroarylation of alkenes and alkynes with tertiary phosphines through P(III)-chelation assisted C-H activation affording a library of functionalized phosphines which hold potential in catalytic applications.

Dingyi Wang
Ben Dong
Zhuangzhi Shi
ResearchOpen Access06 Aug 2019
Nature Communications

Volume: 10, P: 1-10
Reactive oxygen species-responsive and Raman-traceable hydrogel combining photodynamic and immune therapy for postsurgical cancer treatment

Combined immune checkpoint blockade (ICB) and photodynamic therapies have huge potential but suffer from possible damage of the antibodies. Here, the authors create a ROS-responsive hydrogel that protects the ICB antibodies and allows for sustained co-delivery and demonstrate restrained regrowth of tumours in vivo.

Yiyi Zhang
Sidan Tian
Liang Luo
ResearchOpen Access05 Aug 2022
Nature Communications

Volume: 13, P: 1-15
Novel derivatives of brincidofovir and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine inhibit orthopoxviruses and human adenoviruses more potently than brincidofovir

Yifan Zhang
Yanmin Wan
Wenhong Zhang
ResearchOpen Access11 Apr 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-11
Pre-activated nanoparticles with persistent luminescence for deep tumor photodynamic therapy in gallbladder cancer

Phototherapy of deep tumors suffers from many obstacles, such as limited near-infrared tissue penetration depth and low accumulation efficiency within the target sites. Here, the authors report stimuli sensitive tumor-targeted photodynamic nanoparticles with persistent luminescence for the treatment of deep tumors.

Sarun Juengpanich
Shijie Li
Mingyu Chen
ResearchOpen Access14 Sept 2023
Nature Communications

Volume: 14, P: 1-16
Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth

Neonates and infants infected with HIV generally develop disease rapidly, with early antiretroviral therapy (ART) often failing to achieve a sustained state of ART-free virologic remission. Here, the authors study viral reservoirs in neonatal macaques with early initiation of ART and an integrase inhibitor.

Xiaolei Wang
Eunice Vincent
Huanbin Xu
ResearchOpen Access16 Aug 2022
Nature Communications

Volume: 13, P: 1-12
The homeobox transcription factor DUXBL controls exit from totipotency

The transcription factor double homeobox protein (DUX) induces a totipotency-specific regulatory program, including the upregulation of DUXBL. DUXBL subsequently accesses DUX-bound regions and interacts with TRIM24 and TRIM33, thus contributing to totipotency exit.

Maria Vega-Sendino
Felipe F. Lüttmann
Sergio Ruiz
Research20 Mar 2024
Nature Genetics

Volume: 56, P: 697-709
Fostering students’ geographical synthetic thinking using geographic subject mind maps

Zhijie Huang
Ye Yang
Xiaoxu Lu
ResearchOpen Access20 Jun 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Unraveling the synergistic effects of Cu-Ag tandem catalysts during electrochemical CO₂ reduction using nanofocused X-ray probes

Combining in situ nanoprobe techniques paves the way for gaining insights into structure-selectivity relations for electrocatalysts. Herein, the dynamic evolution of lattice strain in individual nanoparticles is directly visualized with nanoscale resolution in Cu-Ag tandem catalysts during the electrocatalytic conversion of CO2 into value-added chemicals.

Marvin L. Frisch
Longfei Wu
Peter Strasser
ResearchOpen Access29 Nov 2023
Nature Communications

Volume: 14, P: 1-9
Does people oriented urbanization catch up with land and population urbanization

Tianci Gu
Qingxu Huang
Jiasheng Wang
ResearchOpen Access29 Jul 2025
npj Urban Sustainability

Volume: 5, P: 1-17
Cadmium iodide-mediated allenylation of terminal alkynes with ketones

The allenylation of terminal alkynes is a convenient route to allenes from simple starting materials, though previously limited to formaldehyde and aldehyde substrates. Here a method enabling the use of ketones is reported, giving easy access to trisubstituted allenes.

Xinjun Tang
Can Zhu
Shengming Ma
Research17 Sept 2013
Nature Communications

Volume: 4, P: 1-7
Structural insights into calcium-dependent CIB2-TMC1 interaction in hair cell mechanotransduction

Structural insights into the CIB2-TMC1 complex reveal how calcium regulates cochlear hair cell MET channels and highlight the impact of pathogenic CIB2 variants associated with hearing loss.

Yahong Li
Jiasheng Chen
Chao Wang
ResearchOpen Access25 Feb 2025
Communications Biology

Volume: 8, P: 1-12
Immunoregulatory nanomedicine for respiratory infections

Vaccination and immune-regulation strategies are crucial for the prevention and treatment of respiratory infectious diseases. This Review discusses the design and optimization of nanomedicines for vaccines and immunotherapeutics for respiratory infectious diseases.

Yafang Xiao
Yuanyu Huang
Xing-Jie Liang
Reviews04 Dec 2023
Nature Reviews Bioengineering

Volume: 2, P: 244-259
Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway

Yingbin Liu, Yun Liu, Hui Wang and colleagues perform whole-exome and targeted gene sequencing of gallbladder carcinoma. They identify recurrent somatic alterations in components of the ErbB signaling pathway and show that these alterations are associated with poor clinical outcomes.

Maolan Li
Zhou Zhang
Yingbin Liu
Research06 Jul 2014
Nature Genetics

Volume: 46, P: 872-876
De novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore

Yifan Wang
Yiming Huang
Mengzhi Wang
ResearchOpen Access11 May 2024
Scientific Data

Volume: 11, P: 1-7
Study on sentinel hosts for surveillance of future COVID-19-like outbreaks

Yanjiao Li
Jingjing Hu
Chenglong Xiong
ResearchOpen Access19 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
Up-regulation of PKM2 promote malignancy and related to adverse prognostic risk factor in human gallbladder cancer

Wei Lu
Yang Cao
Yingbin Liu
ResearchOpen Access10 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
3D-Spatial encoding with permanent magnets for ultra-low field magnetic resonance imaging

Michael W. Vogel
Ruben Pellicer Guridi
David C. Reutens
ResearchOpen Access06 Feb 2019
Scientific Reports

Volume: 9, P: 1-9
Bivalent DNA vaccine induces significant immune responses against infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in rainbow trout

Liming Xu
Jingzhuang Zhao
Tongyan Lu
ResearchOpen Access18 Jul 2017
Scientific Reports

Volume: 7, P: 1-11
A Preliminary Study of the Carbon Emissions Reduction Effects of Land Use Control

Xiaowei Chuai
Xianjin Huang
Rongqin Zhao
ResearchOpen Access15 Nov 2016
Scientific Reports

Volume: 6, P: 1-8

Search

Slipknot-gauged mechanical transmission and robotic operation

Allogeneic CD19-targeting T cells for treatment-refractory systemic lupus erythematosus: a phase 1 trial

Rhodium-catalysed direct hydroarylation of alkenes and alkynes with phosphines through phosphorous-assisted C−H activation

Reactive oxygen species-responsive and Raman-traceable hydrogel combining photodynamic and immune therapy for postsurgical cancer treatment

Novel derivatives of brincidofovir and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine inhibit orthopoxviruses and human adenoviruses more potently than brincidofovir

Pre-activated nanoparticles with persistent luminescence for deep tumor photodynamic therapy in gallbladder cancer

Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birth

The homeobox transcription factor DUXBL controls exit from totipotency

Fostering students’ geographical synthetic thinking using geographic subject mind maps

Unraveling the synergistic effects of Cu-Ag tandem catalysts during electrochemical CO₂ reduction using nanofocused X-ray probes

Does people oriented urbanization catch up with land and population urbanization

Cadmium iodide-mediated allenylation of terminal alkynes with ketones

Structural insights into calcium-dependent CIB2-TMC1 interaction in hair cell mechanotransduction

Immunoregulatory nanomedicine for respiratory infections

Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway

De novo transcriptome assembly database for 100 tissues from each of seven species of domestic herbivore

Study on sentinel hosts for surveillance of future COVID-19-like outbreaks

Up-regulation of PKM2 promote malignancy and related to adverse prognostic risk factor in human gallbladder cancer

3D-Spatial encoding with permanent magnets for ultra-low field magnetic resonance imaging

Bivalent DNA vaccine induces significant immune responses against infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in rainbow trout

A Preliminary Study of the Carbon Emissions Reduction Effects of Land Use Control

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