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JMJD2 regulates enhancer–promoter interactions via biomolecular condensate formation

This study presents LoopID, which profiles proteins at targeted interacting enhancer–promoter (E-P) pairs, identifying the histone demethylase JMJD2 as a regulator of E-P interactions through biomolecular condensate formation independent of its catalytic activity.

Shaoshuai Jiang
Xinyi Liu
Junjun Ding
Research16 Dec 2025
Nature Genetics

P: 1-14
Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow

Not all infections induce abscess formation, and tissue abscess typically result from pyrogenic bacterial infections. Here the authors use mouse models to assess bone infection with S. aureus and show that macrophage-derived amphiregulin promotes preadipocyte-to-myofibroblast transition via EGFR/mTOR signalling in peri-abscess microenvironments.

Bingsheng Yang
Jianwen Su
Xianrong Zhang
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-20
Deep adversarial learning identifies ADHD-specific associations between apoptotic genes and white matter microstructure in frontal-striatum-cerebellum circuit

Yilu Zhao
Xiangyu Zheng
Li Yang
ResearchOpen Access26 Aug 2025
Translational Psychiatry

Volume: 15, P: 1-9
Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma

Yunjie Li
Shuya Bai
Yangyang Feng
Research04 Oct 2025
Genes & Immunity

Volume: 26, P: 599-612
Global effects of progress towards Sustainable Development Goals on subjective well-being

While the economic effects of progress towards the Sustainable Development Goals (SDGs) have been studied extensively, this study examines how efforts to achieve balance across the SDGs affect subjective well-being within and across countries.

Jianqing Du
Yali Liu
Bojie Fu
Research08 Feb 2024
Nature Sustainability

Volume: 7, P: 360-367
An IPv6 address fast scanning method based on local domain name association

Yakai Fang
Liancheng Zhang
Wenhao Xia
ResearchOpen Access04 Apr 2025
Scientific Reports

Volume: 15, P: 1-19
Activation of PI3K-AKT pathway prevents steroid-induced osteonecrosis of the femoral head via inhibiting Cuproptosis

Shihua Gao
Haoran Zhu
Hu Li
ResearchOpen Access15 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
USP10 deubiquitinates Tau, mediating its aggregation

Zhen Wei
Kuan Zeng
Xiaochuan Wang
ResearchOpen Access20 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-12
National survey on the current status of airway management in China

Yuewen He
Zhengze Zhang
Wuhua Ma
ResearchOpen Access07 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Gut Dysbiosis with Minimal Enteritis Induced by High Temperature and Humidity

Song Chen
Yuhua Zheng
Huanhuan Luo
ResearchOpen Access10 Dec 2019
Scientific Reports

Volume: 9, P: 1-10

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JMJD2 regulates enhancer–promoter interactions via biomolecular condensate formation

Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow

Deep adversarial learning identifies ADHD-specific associations between apoptotic genes and white matter microstructure in frontal-striatum-cerebellum circuit

Post-translational acylation modulates immunosuppression and immunotherapy efficacy in hepatocellular carcinoma

Global effects of progress towards Sustainable Development Goals on subjective well-being

An IPv6 address fast scanning method based on local domain name association

Activation of PI3K-AKT pathway prevents steroid-induced osteonecrosis of the femoral head via inhibiting Cuproptosis

USP10 deubiquitinates Tau, mediating its aggregation

National survey on the current status of airway management in China

Gut Dysbiosis with Minimal Enteritis Induced by High Temperature and Humidity

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