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Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection

Cutaneous tuberculosis is an infectious disease associated with extracellular matrix remodeling and granuloma-driven fibrosis. Here, the authors present an in vitro model of this disease using skin organoids infected with Mycobacterium tuberculosis, and describe infection-induced alterations in specific pathways and cell populations.

Liang Yue
Yating Liang
Yingxia Tan
ResearchOpen Access02 Dec 2025
Nature Communications

Volume: 16, P: 1-16
Non-linear relationship between social jetlag and depressive symptoms among Chinese college students

Jing Luo
Jinyou Yang
Song Lin
ResearchOpen Access26 May 2025
Scientific Reports

Volume: 15, P: 1-8
A single gene integrates sex and hormone regulators into sexual attractiveness

A multidisciplinary approach, including genetics and behavioural assays, identifies a single gene, CYP4PC1, which integrates both sex differentiation and hormone signalling with sexual attractiveness in the German cockroach.

Nan Chen
Yong-Jun Liu
Sheng Li
Research04 Jul 2022
Nature Ecology & Evolution

Volume: 6, P: 1180-1190
Brown adipose tissue-derived FGF21 mediates the cardioprotection of dexmedetomidine in myocardial ischemia/reperfusion injury

Yi Ding
Jiabao Su
Jiru Zhang
ResearchOpen Access07 Aug 2024
Scientific Reports

Volume: 14, P: 1-16
Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s disease

Longfei Wang
Jiru Han
Melanie Bahlo
ResearchOpen Access14 Nov 2024
npj Parkinson's Disease

Volume: 10, P: 1-10
Potential use of molecular and structural characterization of the gut bacterial community for postmortem interval estimation in Sprague Dawley rats

Huan Li
Siruo Zhang
Jiru Xu
ResearchOpen Access08 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
Retinal VIP-amacrine cells: their development, structure, and function

Xuhong Zhang
Xiaoyu Wang
Ye Shen
Reviews08 Dec 2023
Eye

Volume: 38, P: 1065-1076

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Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection

Non-linear relationship between social jetlag and depressive symptoms among Chinese college students

A single gene integrates sex and hormone regulators into sexual attractiveness

Brown adipose tissue-derived FGF21 mediates the cardioprotection of dexmedetomidine in myocardial ischemia/reperfusion injury

Peripheral immune cell abundance differences link blood mitochondrial DNA copy number and Parkinson’s disease

Potential use of molecular and structural characterization of the gut bacterial community for postmortem interval estimation in Sprague Dawley rats

Retinal VIP-amacrine cells: their development, structure, and function

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