Molecular editing allows structures to be built up in terms of complexity, or changed or pruned one atom at a time using transformations which are mild and selective enough to be employed at the late stages of a synthetic sequence. In this Review, a subclass of molecular editing reactions termed ‘single-atom skeletal editing’ are described, with a particular focus on heterocycles.
- Justin Jurczyk
- Jisoo Woo
- Mark D. Levin