Methods: Spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) were subjected to unilateral adrenal ablation with injection of ethanol or a sham procedure. Blood pressure was monitored for 24 weeks. Results: Adrenal ablation significantly lowered systolic and diastolic blood pressure of SHR but not WKY from 4 to 24 weeks after the procedure. Conclusion: Unilateral debulking of the adrenal gland using ethanol ablation is a promising therapeutic strategy for treating hypertension.
- Xinquan Wang
- Tao Luo
- Peijian Wang
