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Showing 1–3 of 3 results
Advanced filters: Author: Jonathan I. D. Hamley Clear advanced filters

  • Drugs for filariases are under development and clinical trial simulators could help to inform the design of clinical trials. Here, Walker et al. use an individual-based onchocerciasis transmission model to project trial outcomes of a hypothetical macrofilaricidal drug, resolving key design choices.

    • Martin Walker
    • Jonathan I. D. Hamley
    • Maria-Gloria Basáñez
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Onchocerciasis is a vector-borne disease endemic to parts of sub-Saharan Africa and associated with substantial morbidity including reports of onchocerciasis-associated epilepsy. Here, the authors use mathematical modelling to assess the impact of community-directed treatment with ivermectin on onchocerciasis-associated epilepsy.

    • Jacob N. Stapley
    • Jonathan I. D. Hamley
    • Maria-Gloria Basáñez
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11