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Showing 1–2 of 2 results
Advanced filters: Author: Joonwoo Rhee Clear advanced filters
  • Cubosomes, cubic-phase lipid nanoparticles, are of interest for delivery application but have failed in the delivery of long RNA. Here, the authors report on a premixing strategy which allows for the loading of long RNA into cubosomes with the advantage of consistent delivery after room temperature storage.

    • Harin Jin
    • Iji Seo
    • Hojun Kim
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11
  • Muscle atrophy is associated with ageing, but the underlying molecular mechanisms are not well understood. Here, they authors show that ablation of the E3 ubiquitin ligase Mib1 is important for myofibre maintenance via a mechanism that involves targeting and degradation of Actn3, and that Mib1 ablation in mice induces muscle atrophy which can be rescued by knockown of Actn3 expression.

    • Ji-Yun Seo
    • Jong-Seol Kang
    • Young-Yun Kong
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15