Advances in nanoparticle engineering, and in understanding of the importance of nanoparticle characteristics such as size, shape and surface properties for biological interactions, are creating new opportunities for the development of nanoparticles for therapeutic applications such as targeted drug delivery. Petros and DeSimone review the impact of nanoparticle characteristics on their biological properties and recent progress in the rational design of nanoparticle therapeutics, discussing the challenges to realizing their potential.
- Robby A. Petros
- Joseph M. DeSimone