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Showing 1–24 of 24 results
Advanced filters: Author: Joshua Daw Clear advanced filters

  • To study cognition, researchers have traditionally used laboratory-based experiments, but games offer a valuable alternative: they are intuitive and enjoyable. In this Perspective, Schulz et al. discuss the advantages and drawbacks of games and give recommendations for researchers.

    • Kelsey Allen
    • Franziska Brändle
    • Eric Schulz
    Reviews
    Nature Human Behaviour
    Volume: 8, P: 1035-1043

  • A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

    • Loïc Yengo
    • Sailaja Vedantam
    • Joel N. Hirschhorn
    ResearchOpen Access
    Nature
    Volume: 610, P: 704-712

  • Poaching undermines the effectiveness of marine protected areas, where enforcement capacity is limited. In this study, fishers adjacent to MPAs were surveyed, and it was found that about half had observed poaching, but that most do not react so as to avoid conflict, or because they feel that this is either not their responsibility or that poaching is a survival strategy.

    • Brock J. Bergseth
    • Georgina G. Gurney
    • Joshua E. Cinner
    Research
    Nature Sustainability
    Volume: 1, P: 421-426

  • A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

    • Sarah E. Graham
    • Shoa L. Clarke
    • Cristen J. Willer
    Research
    Nature
    Volume: 600, P: 675-679

    • Rosamund Daw
    • Joshua Finkelstein
    Editorial
    Nature
    Volume: 442, P: 367

    • Rosamund Daw
    • Joshua Finkelstein
    • Magdalena Helmer
    Editorial
    Nature
    Volume: 488, P: 293

  • Mohebi et al. report that dopamine (DA) pulses in different rat striatal subregions signal prediction errors across different timescales. In this way, one learning process may achieve a range of adaptive behaviors.

    • Ali Mohebi
    • Wei Wei
    • Joshua D. Berke
    ResearchOpen Access
    Nature Neuroscience
    Volume: 27, P: 737-746

  • Meta-analyses in up to 1.3 million individuals identify 87 rare-variant associations with blood pressure traits. On average, rare variants exhibit effects ~8 times larger than the mean effects of common variants and implicate candidate causal genes at associated regions.

    • Praveen Surendran
    • Elena V. Feofanova
    • Joanna M. M. Howson
    Research
    Nature Genetics
    Volume: 52, P: 1314-1332

  • An analysis of quantitative sociological data reveals that adaptive capacity has increased in coastal fishing communities in Kenya, but that underprivileged segments of society remain vulnerable to the impacts of climate change.

    • Joshua E. Cinner
    • Cindy Huchery
    • Edward H. Allison
    Research
    Nature Climate Change
    Volume: 5, P: 872-876

  • Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

    • Andrew R Wood
    • Tonu Esko
    • Timothy M Frayling
    Research
    Nature Genetics
    Volume: 46, P: 1173-1186

  • Genome-wide association meta-analyses of waist-to-hip ratio adjusted for body mass index in more than 224,000 individuals identify 49 loci, 33 of which are new and many showing significant sexual dimorphism with a stronger effect in women; pathway analyses implicate adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution.

    • Dmitry Shungin
    • Thomas W. Winkler
    • Karen L Mohlke
    Research
    Nature
    Volume: 518, P: 187-196

  • A genome-wide association study and Metabochip meta-analysis of body mass index (BMI) detects 97 BMI-associated loci, of which 56 were novel, and many loci have effects on other metabolic phenotypes; pathway analyses implicate the central nervous system in obesity susceptibility and new pathways such as those related to synaptic function, energy metabolism, lipid biology and adipogenesis.

    • Adam E. Locke
    • Bratati Kahali
    • Elizabeth K. Speliotes
    Research
    Nature
    Volume: 518, P: 197-206

  • Midbrain dopamine neurons have been implicated in two related but distinct processes: reward learning and action generation. By combining an operant learning task in mice with recordings from projection-defined dopamine neurons, the authors found that dopamine neurons targeting different parts of the striatum carry different information about rewards and chosen actions.

    • Nathan F Parker
    • Courtney M Cameron
    • Ilana B Witten
    Research
    Nature Neuroscience
    Volume: 19, P: 845-854

  • The Editorial Board and Editorial Team are delighted to present a selection of short Research Highlights describing some of our favourite Communications Engineering publications of 2023.

    • Miranda Vinay
    • Liwen Sang
    • Chaoran Huang
    ReviewsOpen Access
    Communications Engineering
    Volume: 2, P: 1-7

  • Diorganozinc reagents (ZnR2, e.g. R = Et, Ph, C6F5) are widely used as Lewis acid catalysts or Lewis base reagents, however, descriptors for predicting the influence of the R substituent are scarce. Here, by using liquid-phase X-ray spectroscopy, the authors have identified the geometric structures of diorganozincs in weakly coordinating solvents and then established Zn-specific descriptors to quantify the properties of their underlying Lewis acidity/basicity.

    • Lewis G. Parker
    • Frances K. Towers Tompkins
    • Kevin R. J. Lovelock
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-13

  • Daniel Chasman, Daniel Levy, Christopher Newton-Cheh, Georg Ehret and colleagues perform an association meta-analysis for blood pressure in ∼330,000 individuals and identify 31 new risk loci, implicating biological pathways related to vascular function and cardiometabolic traits. Their findings highlight potential therapeutic strategies for hypertension, emphasizing a link with cardiometabolic risk.

    • Chunyu Liu
    • Aldi T Kraja
    • Daniel I Chasman
    Research
    Nature Genetics
    Volume: 48, P: 1162-1170

  • Learning to predict reward is thought to be driven by dopaminergic prediction errors, which reflect discrepancies between actual and expected value. Here the authors show that learning to predict neutral events is also driven by prediction errors and that such value-neutral associative learning is also likely mediated by dopaminergic error signals.

    • Melissa J Sharpe
    • Chun Yun Chang
    • Geoffrey Schoenbaum
    Research
    Nature Neuroscience
    Volume: 20, P: 735-742

  • The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.

    • Rotem Botvinik-Nezer
    • Felix Holzmeister
    • Tom Schonberg
    Research
    Nature
    Volume: 582, P: 84-88

  • Learning which environmental cues predict harm is paramount to survival, yet evidence for these associations is often ambiguous. The authors demonstrate a critical role for the amygdala in evaluating such ambiguities and show that a computational framework based on structure learning can explain this process.

    • Tamas J Madarasz
    • Lorenzo Diaz-Mataix
    • Joshua P Johansen
    Research
    Nature Neuroscience
    Volume: 19, P: 965-972