Nature Search

Investigating the analytical robustness of the social and behavioural sciences

When 100 social and behavioural science claims were examined, 34% of reanalyses closely matched the original results, with 74% reaching the same conclusion, revealing limited robustness of single-path analyses and the need to address analytical uncertainty.

Balazs Aczel
Barnabas Szaszi
Brian A. Nosek
Research01 Apr 2026
Nature

Volume: 652, P: 135-142
Quarter- and half-filled quantum Hall states and their topological orders revealed by daughter states in bilayer graphene

Bilayer graphene has been shown to host fractional quantum Hall states. Here, the authors observe the fractional quantum Hall states at quarter- and half-filled Landau levels and the alternation of anti-Pfaffian and Pfaffian phases at half fillings.

Ravi Kumar
André Haug
Yuval Ronen
ResearchOpen Access06 Aug 2025
Nature Communications

Volume: 16, P: 1-8
Europa’s ice thickness and subsurface structure characterized by the Juno microwave radiometer

Microwave observations of Jupiter’s moon Europa reveal subsurface properties of the ice shell covering a purported global ocean. The shell is 29 ± 10 km thick, with fractures or pores a few centimetres across that extend hundreds of metres deep.

S. M. Levin
Z. Zhang
R. Akiba
ResearchOpen Access17 Dec 2025
Nature Astronomy

Volume: 10, P: 84-91
Early Oldowan technology thrived during Pliocene environmental change in the Turkana Basin, Kenya

Here, the authors present archaeology of the Namorotukunan site in Kenya’s Turkana Basin that demonstrates adaptive shifts in hominin tool-making behaviour spanning 300,000 years and increasing environmental variability. They contextualize these findings with paleoenvironmental proxies, dating, and geological descriptions.

David R. Braun
Dan V. Palcu Rolier
Susana Carvalho
ResearchOpen Access04 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Chemical reactivity from the perspective of enthalpic coupling

This Perspective analyses chemical reactivity through enthalpic coupling between bond making and bond breaking in elementary steps. Using enthalpic maps, mechanisms are compared, revealing shared energetic patterns and showing how targeted modifications of elementary steps can generate new reactivity. This framework offers a route towards systematic reaction discovery.

Chelsey Brien
Andrei K. Yudin
Reviews12 Mar 2026
Nature Synthesis

Volume: 5, P: 321-329
Radio studies of the double QSO, 0957 + 561A, B

G. G. Pooley
I. W. A. Browne
D. Walsh
Research01 Aug 1979
Nature

Volume: 280, P: 461-464
Some Aspects of the Fibrinogen-Fibrin Transition

K. LAKI
JULES A. GLADNER
J. E. FOLK
Research27 Aug 1960
Nature

Volume: 187, P: 758-761
Determination of the spin and parity of all-charm tetraquarks

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

A. Hayrapetyan
V. Makarenko
A. Snigirev
ResearchOpen Access03 Dec 2025
Nature

Volume: 648, P: 58-63
The impact of renewable energy on CO₂ emissions in Middle Eastern and BRICS economies

Amsalu K. Addis
ResearchOpen Access14 Jan 2026
Humanities and Social Sciences Communications

Volume: 13, P: 1-20
Microscopic Examination of Highly Radioactive Fall-Out Particles

T. MAMURO
A. FUJITA
K. YOSHIKAWA
Research10 Nov 1962
Nature

Volume: 196, P: 529-531
Topological phase transition between Jain states and daughter states of the ν = 1/2 fractional quantum Hall state

The nature of the fractional quantum Hall state when the lowest Landau level is half-filled remains controversial. Now, the observation of a topological phase transition at related filling fractions suggests that the half-filled state is non-Abelian.

S. K. Singh
C. Wang
M. Shayegan
Research27 May 2024
Nature Physics

Volume: 20, P: 1247-1252
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

Here authors show loss of AKAP11, a strong genetic risk factor for bipolar disorder and schizophrenia, disrupts PKA proteostasis and signaling, leading to widespread transcriptomic alterations across the brain, particularly in striatal neurons, as well as altered behavior.

Bryan J. Song
Yang Ge
Morgan Sheng
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-25
Phosphorylation of Pyridoxine by Escherichia coli B

K. V. KENNY
W. B. DEMPSEY
Research25 Feb 1967
Nature

Volume: 213, P: 830
Involvement of a Phage T4 σ Factor and an Anti-terminator Protein in the Transcription of Early T4 Genes in vivo

D. A. SCHMIDT
A. J. MAZAITIS
E. K. F. BAUTZ
Research14 Mar 1970
Nature

Volume: 225, P: 1012-1016
Control of Translation by T4 Phage: Altered Binding of Disfavoured Messengers

SHYAM K. DUBE
PHILIP S. RUDLAND
Research30 May 1970
Nature

Volume: 226, P: 820-823
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction

Multi-ancestry genome-wide and transcriptome-wide association studies of aortic stenosis identify more than 200 independent risk loci and provide insights into its genetic architecture.

Aeron M. Small
Ta-Yu Yang
George Thanassoulis
ResearchOpen Access19 Dec 2025
Nature Genetics

Volume: 58, P: 57-66
Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

Suparmolecular polymers are built by monomers via non-covalent bonds, whilst the pathway of their nucleation processes is not yet clear. Here, Levin et al.show that the self-assembly of monomers proceeds through a series of metastable states, which are energetically governed by Ostwald’s rule of stages.

Aviad Levin
Thomas O. Mason
Ehud Gazit
Research13 Nov 2014
Nature Communications

Volume: 5, P: 1-8
Elliptic anisotropy measurement of the f₀(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A. Hayrapetyan
A. Tumasyan
A. Zhokin
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Effect of Antilymphocytic Antibody and Antibody Fragments on Human Lymphocytes in vitro

M. F. A. WOODRUFF
B. REID
K. JAMES
Research05 Aug 1967
Nature

Volume: 215, P: 591-594
Multidimensional specialization and generalization are pervasive in soil prokaryotes

Analyses of soil microbiomes across the United States reveal pervasive multidimensional specialization and generalization across prokaryotic communities impacting evolutionary trajectories, microbial dominance and community roles.

Damian J. Hernandez
Kasey N. Kiesewetter
Michelle E. Afkhami
Research07 Aug 2023
Nature Ecology & Evolution

Volume: 7, P: 1408-1418
Increased Dihydrofolate Reductase Activity as a Possible Basis of Drug Resistance in Leukæmia

D. K. MISRA
STEWART R. HUMPHREYS
ELIZABETH J. CRAWFORD
Research07 Jan 1961
Nature

Volume: 189, P: 39-42
Regularities in the Spark Spectrum of Silver

K. MAJUMDAR
Research24 Dec 1927
Nature

Volume: 120, P: 918
Contaminant Trapping Behind Large Dams: A Mini-Review

Sierra Rayne
Ken Friesen
ResearchOpen Access24 Mar 2009
Nature Precedings

P: 1
Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors

Dual cyclin A/B RxL inhibitors selectively kill small cell lung cancer cells and other cancer cells with high E2F activity.

Shilpa Singh
Catherine E. Gleason
Matthew G. Oser
ResearchOpen Access20 Aug 2025
Nature

Volume: 646, P: 734-745
Optically active benzo[c]phenanthrene diol epoxides bind extensively to adenine in DNA

A. Dipple
M. A. Pigott
D. M. Jerina
Research11 Jun 1987
Nature

Volume: 327, P: 535-536
Unique Amyloid Protein Subunit common to Different Types of Amyloid Fibril

G. HUSBY
J. B. NATVIG
H. HÖST
Research10 Aug 1973
Nature

Volume: 244, P: 362-364
Synthesis of Pigment in Symbiotic Chloroplasts

ROBERT K. TRENCH
DAVID C. SMITH
Research11 Jul 1970
Nature

Volume: 227, P: 196-197
Diffuse X-Ray Reflexions

K. LONSDALE
Research19 Apr 1941
Nature

Volume: 147, P: 481-482
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing

Michael K. Jones
Hongtao Wang
Andrzej S. Tarnawski
Research01 Dec 1999
Nature Medicine

Volume: 5, P: 1418-1423
BRCA2 deficiency and replication stress drive APOBEC3-Mediated genomic instability

Here the authors reveal how replication stress in BRCA2-deficient cells triggers a mutagenic cycle of APOBEC3B upregulation, uracil accumulation at stalled forks, and DNA damage, uncovering a self-reinforcing loop that fuels genomic instability.

Kathy Situ
Haohui Duan
Shailja Pathania
ResearchOpen Access29 Oct 2025
Nature Communications

Volume: 16, P: 1-24
Intrathecal chemotherapy with ACNU for meningeal gliomatosis

TK Yoshida
E Beuls
V Sturm
Research01 Dec 1992
British Journal of Cancer

Volume: 66, P: 999-1004
Monoclonal antibody levels and protection from COVID-19

Monoclonal antibodies (mAbs) have shown efficacy against SARS-CoV-2 infection in clinical trials. Here the authors model the dose-response relationship between the dose of mAbs and protection from symptomatic SARS-CoV-2 infection. Further, the protection is comparable to that achieved by vaccination.

Eva Stadler
Martin T. Burgess
David S. Khoury
ResearchOpen Access28 Jul 2023
Nature Communications

Volume: 14, P: 1-9
Input–output maps are strongly biased towards simple outputs

Algorithmic information theory measures the complexity of strings. Here the authors provide a practical bound on the probability that a randomly generated computer program produces a given output of a given complexity and apply this upper bound to RNA folding and financial trading algorithms.

Kamaludin Dingle
Chico Q. Camargo
Ard A. Louis
ResearchOpen Access22 Feb 2018
Nature Communications

Volume: 9, P: 1-7
Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome

The Treacher Collins Syndrome Collaborative Group
Jill Dixon
John J. Wasmuth
Research01 Feb 1996
Nature Genetics

Volume: 12, P: 130-136
Trends and seasonal cycles in the isotopic composition of nitrous oxide since 1940

The atmospheric nitrous oxide concentration has increased by 20% since 1750. Analyses of Antarctic firn and archived air samples reveal seasonal cycles in the isotopic signature of nitrous oxide, which can help to disentangle the contribution of surface sources.

S. Park
P. Croteau
C. M. Trudinger
Research11 Mar 2012
Nature Geoscience

Volume: 5, P: 261-265
Overexpression of E2F‐1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

J. Fueyo
C. Gomez-Manzano
A. P. Kyritsis
Research01 Jun 1998
Nature Medicine

Volume: 4, P: 685-690
Distribution of Guanylic Acid Residues in Tobacco Mosaic Virus Nucleic Acid

K. K. REDDI
Research01 Oct 1960
Nature

Volume: 188, P: 60-61
DNA glycosylases provide antiviral defence in prokaryotes

A screen utilizing an environmental DNA library in Escherichia coli is used to identify Brig1, a previously unknown anti-phage defence system with homologues across distinct clades of bacteria.

Amer A. Hossain
Ying Z. Pigli
Luciano A. Marraffini
ResearchOpen Access17 Apr 2024
Nature

Volume: 629, P: 410-416
Isolation and structure of dynorphin, an opioid peptide, from porcine duodenum

S. Tachibana
K. Araki
S. Yoshida
Research28 Jan 1982
Nature

Volume: 295, P: 339-340
Sensitive near point-of-care detection of asymptomatic and submicroscopic Plasmodium falciparum infections in African endemic countries

Limited diagnostic capacity for asymptomatic individuals hinders malaria elimination efforts in Africa. Here, the authors present a near point-of-care method based on colorimetric LAMP detection that outperforms expert microscopy and commercial rapid diagnostic tests for Plasmodium detection in asymptomatic and submicroscopic individuals.

Dimbintsoa Rakotomalala Robinson
Ivana Pennisi
Asadu Sserwanga
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-13
Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens

CURTIS C. HARRIS
IH CHANG Hsu
JAMES K. SELKIRK
Research13 Apr 1978
Nature

Volume: 272, P: 633-634
Persistence and reversal of plasmid-mediated antibiotic resistance

It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence of antibiotics.

Allison J. Lopatkin
Hannah R. Meredith
Lingchong You
ResearchOpen Access22 Nov 2017
Nature Communications

Volume: 8, P: 1-10
Gene flow in Plantago I. Gene flow and neighbourhood size in P. lanceolata

M Bos
H Harmens
K Vrieling
Research01 Feb 1986
Heredity

Volume: 56, P: 43-54
Emergent patterns of patchiness differ between physical and planktonic properties in the ocean

What can we learn from spatial patterns in the ocean? This study suggests planktonic patterns are uncorrelated from physical patchiness, poorly captured from satellite observations, and an underutilized window into ocean biogeochemistry.

Patrick Clifton Gray
Emmanuel Boss
Yoav Lehahn
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-12
VLBI observations of hot spots in the lobes of distant radio sources

V. K. Kapahi
R. T. Schilizzi
Research01 Feb 1979
Nature

Volume: 277, P: 610-615
Positions of galactic X-ray sources: 0° < l^II < 20°

R. E. DOXSEY
K. M. V. APPARAO
J. G. JERNIGAN
Research15 Dec 1977
Nature

Volume: 270, P: 586-588
Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA

Alicia K Byrd
Kevin D Raney
Research16 May 2004
Nature Structural & Molecular Biology

Volume: 11, P: 531-538
Glutamate and γ-Aminobutyric Acid in Brain

K. KRNJEVIĆ
Research10 Oct 1970
Nature

Volume: 228, P: 119-124
Whistling Sand of Porth Oer, Caernarvonshire

K. RIDGWAY
R. RUPP
Research11 Apr 1970
Nature

Volume: 226, P: 158-159

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