During the 2015–2016 outbreak, Zika virus infection was linked to birth defects. Here, the authors show that epidemic strains cause less severe disease in mouse embryos than pre-epidemic strains and conclude that less severe disease leads to higher fetal survival rates but results in noticeable birth defects.
- Maïlis Darmuzey
- Franck Touret
- Suzanne J. F. Kaptein