Nature Search

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

Here, Marcado-Evans et al show that gestational diabetes enhances group B Streptococcus infection through altering host-microbe dynamics, disrupting maternal immunity, and perturbing the vaginal microbiota in a murine pregnancy model.

Vicki Mercado-Evans
Marlyd E. Mejia
Kathryn A. Patras
ResearchOpen Access03 Feb 2024
Nature Communications

Volume: 15, P: 1-20
Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition

Resistance to menin inhibitors often occurs in the initially sensitive MLL-rearranged (MLLr) leukemias. Here authors discover that inhibition of guanine nucleotide biosynthesis leads to myeloid differentiation and sensitization to menin inhibitors in leukemia stem cells of MLLr leukemia.

Xiangguo Shi
Minhua Li
Daisuke Nakada
ResearchOpen Access18 Mar 2025
Nature Communications

Volume: 16, P: 1-20
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Global chemical effects of the microbiome include new bile-acid conjugations

Metabolomics data from germ-free and specific-pathogen-free mice reveal effects of the microbiome on host chemistry, identifying conjugations of bile acids that are also enriched in patients with inflammatory bowel disease or cystic fibrosis.

Robert A. Quinn
Alexey V. Melnik
Pieter C. Dorrestein
Research26 Feb 2020
Nature

Volume: 579, P: 123-129
A cross-systems primer for synthetic microbial communities

Here the authors outline best practices for the development, implementation and evaluation of synthetic microbial communities (or SynComs) across different systems.

Elijah C. Mehlferber
Gontran Arnault
Britt Koskella
Reviews30 Oct 2024
Nature Microbiology

Volume: 9, P: 2765-2773
Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

Marlyd E. Mejia
Vicki Mercado-Evans
Kathryn A. Patras
ResearchOpen Access20 Nov 2023
npj Biofilms and Microbiomes

Volume: 9, P: 1-16

Search

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition

Genomic investigations of unexplained acute hepatitis in children

Adeno-associated virus 2 infection in children with non-A–E hepatitis

Global chemical effects of the microbiome include new bile-acid conjugations

A cross-systems primer for synthetic microbial communities

Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

Search

Quick links

Search

Filter By:

Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota

Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition

Genomic investigations of unexplained acute hepatitis in children

Adeno-associated virus 2 infection in children with non-A–E hepatitis

Global chemical effects of the microbiome include new bile-acid conjugations

A cross-systems primer for synthetic microbial communities

Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

Search

Quick links