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Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

Polygenic risk scores for Alzheimer’s disease derived from individuals of European ancestry can show improved performance in multiancestry settings after incorporating genome-wide association summary statistics from diverse populations.

Aude Nicolas
Richard Sherva
Jean-Charles Lambert
ResearchOpen Access18 Jun 2025
Nature Genetics

Volume: 57, P: 1598-1610
An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals

Anna Offersgaard
Carlos R. Duarte Hernandez
Judith Margarete Gottwein
ResearchOpen Access24 Jul 2024
Scientific Reports

Volume: 14, P: 1-18
Subtype and cell type specific expression of lncRNAs provide insight into breast cancer

Long non-coding RNAs (lncRNAs) have been shown to be involved in breast cancer pathogenesis through regulation of multiple steps of gene expression. lncRNA expression patterns are also associated with breast cancer clinicopathological features in large population-based cohorts.

Sunniva Stordal Bjørklund
Miriam Ragle Aure
Vessela N. Kristensen
ResearchOpen Access18 Aug 2022
Communications Biology

Volume: 5, P: 1-14

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