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Scientific Reports (12)
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Showing 1–20 of 20 results

Advanced filters: Author: Keiichi Ohshima Clear advanced filters

Translating spatial transcriptomic signatures in adenosquamous carcinoma into bulk prognostic biomarkers in lung adenocarcinoma: a bottom-up approach

Keiichi Hatakeyama
Takuya Kawata
Ken Yamaguchi
ResearchOpen Access23 Jan 2026
npj Precision Oncology

P: 1-13
Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

Seongman Kang
Adam Jaworski
Robert D. Wells
Research01 Jun 1995
Nature Genetics

Volume: 10, P: 213-218
Novel CYP2A7/CYP2A6 germline hybrids associated with mutation burden in lung cancer revealed by whole-genome long-read sequencing

Sumiko Ohnami
Keiichi Hatakeyama
Ken Yamaguchi
ResearchOpen Access21 Nov 2025
Scientific Reports

Volume: 15, P: 1-10
Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content

Keiichi Hatakeyama
Koji Muramatsu
Ken Yamaguchi
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-8
Localization of epidermal growth factor receptor-mutations using PNA:DNA probes in clinical specimens from patients with non-small cell lung cancer

Haruo Miyata
Hajime Shigeto
Yasuto Akiyama
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
JCGA: the Japanese version of the Cancer Genome Atlas and its contribution to the interpretation of gene alterations detected in clinical cancer genome sequencing

Masakuni Serizawa
Maki Mizuguchi
Ken Yamaguchi
ResearchOpen Access30 Sept 2021
Human Genome Variation

Volume: 8, P: 1-4
Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations

Keiichi Hatakeyama
Koji Muramatsu
Ken Yamaguchi
ResearchOpen Access22 Feb 2022
Scientific Reports

Volume: 12, P: 1-8
Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1

Akane Naruoka
Sumiko Ohnami
Ken Yamaguchi
ResearchOpen Access27 Apr 2017
Human Genome Variation

Volume: 4, P: 1-6
Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance

Reversible internal RNA phosphrylation contributes to thermal stability and nuclease resistance of tRNA, and cellular thermotolerance of hyperthermophiles.

Takayuki Ohira
Keiichi Minowa
Tsutomu Suzuki
ResearchOpen Access27 Apr 2022
Nature

Volume: 605, P: 372-379
Evaluation of whole genome sequencing utility in identifying driver alterations in cancer genome

Takeshi Nagashima
Ken Yamaguchi
Yasuto Akiyama
ResearchOpen Access12 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

Keiichi Ohshima
Keiichi Hatakeyama
Ken Yamaguchi
ResearchOpen Access04 Apr 2017
Scientific Reports

Volume: 7, P: 1-13
Characterization of pancreatic cancer with ultra-low tumor mutational burden

Taisuke Imamura
Ryo Ashida
Ken Yamaguchi
ResearchOpen Access16 Mar 2023
Scientific Reports

Volume: 13, P: 1-12
Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes

Sumiko Ohnami
Akane Naruoka
Ken Yamaguchi
ResearchOpen Access26 Oct 2022
Scientific Reports

Volume: 12, P: 1-9
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations

Keiichi Hatakeyama
Keiichi Ohshima
Ken Yamaguchi
ResearchOpen Access07 Jun 2018
Scientific Reports

Volume: 8, P: 1-12
Stratification of G2 pancreatic neuroendocrine tumors using a Ten Percent Ki-67 index cut-off based on clinicopathological and molecular analyses

Yumiko Kageyama
Ryo Ashida
Ken Yamaguchi
ResearchOpen Access29 May 2025
Scientific Reports

Volume: 15, P: 1-12
Severity estimation of very-long-chain acyl-CoA dehydrogenase deficiency via ¹³C-fatty acid loading test

Keiichi Sugihara
Miori Yuasa
Yosuke Shigematsu
Research08 Feb 2022
Pediatric Research

Volume: 92, P: 1391-1399
Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Takuya Yokoyama
Masaki Yukuhiro
Masatoshi Fujita
ResearchOpen Access14 Nov 2019
Scientific Reports

Volume: 9, P: 1-13
CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma

The oncogenic ability of mutant CARD11 (E626K), one of most frequently mutated genes in adult T-cell leukemia and its cooperative effect with HBZ expression, using the CD4 promoter-driven HBZ transgenic mouse model, is investigated.

Takuro Kameda
Kotaro Shide
Kazuya Shimoda
ResearchOpen Access29 Nov 2022
Communications Biology

Volume: 5, P: 1-15
Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4⁺ T cells and disease activity

Yasuo Nagafuchi
Hirofumi Shoda
Kazuhiko Yamamoto
ResearchOpen Access07 Jul 2016
Scientific Reports

Volume: 6, P: 1-11
Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines

Akiko Kimura
Masahide Ohmichi
Yuji Murata
Research29 Mar 2004
Oncogene

Volume: 23, P: 4505-4515

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Translating spatial transcriptomic signatures in adenosquamous carcinoma into bulk prognostic biomarkers in lung adenocarcinoma: a bottom-up approach

Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

Novel CYP2A7/CYP2A6 germline hybrids associated with mutation burden in lung cancer revealed by whole-genome long-read sequencing

Tumor cell enrichment by tissue suspension improves sensitivity to copy number variation in diffuse gastric cancer with low tumor content

Localization of epidermal growth factor receptor-mutations using PNA:DNA probes in clinical specimens from patients with non-small cell lung cancer

JCGA: the Japanese version of the Cancer Genome Atlas and its contribution to the interpretation of gene alterations detected in clinical cancer genome sequencing

Tumor cell enrichment by tissue suspension enables detection of mutations with low variant allele frequency and estimation of germline mutations

Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1

Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance

Evaluation of whole genome sequencing utility in identifying driver alterations in cancer genome

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

Characterization of pancreatic cancer with ultra-low tumor mutational burden

Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes

Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations

Stratification of G2 pancreatic neuroendocrine tumors using a Ten Percent Ki-67 index cut-off based on clinicopathological and molecular analyses

Severity estimation of very-long-chain acyl-CoA dehydrogenase deficiency via ¹³C-fatty acid loading test

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma

Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4⁺ T cells and disease activity

Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines

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