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Showing 1–3 of 3 results
Advanced filters: Author: Keith J. Mickolajczyk Clear advanced filters
  • The molecular mechanisms underlying natural transformation remain poorly understood. Here, the authors use optical tweezers to show how the periplasmic DNA receptor ComEA drives the inward pulling of DNA by switching between oligomerization states.

    • Joshua I. Santiago
    • Ishtiyaq Ahmed
    • Keith J. Mickolajczyk
    ResearchOpen Access
    Nature Communications
    P: 1-14
  • Kinesins are molecular motors that travel along microtubules through a nucleotide-dependent stepping mechanism. Here the authors present the crystal structure of Zen4 (kinesin-6) in an apo state that sheds light on a key stepping intermediate of kinesin.

    • Ruifang Guan
    • Lei Zhang
    • Zhucheng Chen
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9
  • TRPV are cation channels activated by physical and chemical stimuli. Here the authors show that nicotinamide is a soluble, endogenous agonist for orthologous TRPV channels fromC. elegans and Drosophila, unveiling a metabolic-based regulation for TRPV channel activity.

    • Awani Upadhyay
    • Aditya Pisupati
    • Wendy Hanna-Rose
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11