Nature Search

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

Psychiatric disorders are often accompanied by alterations in BMI and body composition due to changes in eating behaviour and physical activity. Here, Hübel et al. study the genetic overlap between these traits and find that genetic correlations between psychiatric disorders and body composition are sex-specific and evident only in adulthood.

Christopher Hübel
Héléna A. Gaspar
Gerome Breen
ResearchOpen Access18 Dec 2019
Nature Communications

Volume: 10, P: 1-12
Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

Cerebral small vessel disease (CSVD) is a major cause of stroke and associated with structural changes of the brain. Here, Persyn et al. perform genome-wide association studies for magnetic resonance imaging (MRI) markers of CSVD, explore genetic correlations and prioritize candidate genes.

Elodie Persyn
Ken B. Hanscombe
Hugh S. Markus
ResearchOpen Access01 May 2020
Nature Communications

Volume: 11, P: 1-12
The correlation between reading and mathematics ability at age twelve has a substantial genetic component

Understanding the genetic basis of cognitive traits could aid the development of numeracy and literacy skills in children. Here the authors show that reading and mathematics have a large overlapping genetic component and suggest that a child's learning environment has a key role in creating differences between them.

Oliver S. P. Davis
Gavin Band
Chris C. A. Spencer
ResearchOpen Access08 Jul 2014
Nature Communications

Volume: 5, P: 1-6
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

Integration of GWAS and single-cell transcriptomic data from the entire nervous system systematically identifies cell types underlying brain complex traits and provides insights into the etiology of Parkinson’s disease.

Julien Bryois
Nathan G. Skene
Patrick F. Sullivan
Research27 Apr 2020
Nature Genetics

Volume: 52, P: 482-493
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Genome-wide analyses identify eight independent loci associated with anorexia nervosa. Genetic correlations implicate both psychiatric and metabolic components in the etiology of this disorder, even after adjusting for the effects of common variants associated with body mass index.

Hunna J. Watson
Zeynep Yilmaz
Cynthia M. Bulik
Research15 Jul 2019
Nature Genetics

Volume: 51, P: 1207-1214
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa

Zheng-An Lu
Alexander Ploner
Sarah E. Bergen
ResearchOpen Access23 Sept 2025
Molecular Psychiatry

P: 1-10
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Chiara Fabbri
Saskia P. Hagenaars
Cathryn M. Lewis
ResearchOpen Access22 Mar 2021
Molecular Psychiatry

Volume: 26, P: 3363-3373

Search

Filter By:

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants

The correlation between reading and mathematics ability at age twelve has a substantial genetic component

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa

Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Search

Quick links