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Showing 1–11 of 11 results
Advanced filters: Author: Kieren J. Mitchell Clear advanced filters

  • Dire wolves split from living canids around 5.7 million years ago and originated in the New World isolated from the ancestors of grey wolves and coyotes, which evolved in Eurasia and colonized North America only relatively recently.

    • Angela R. Perri
    • Kieren J. Mitchell
    • Laurent A. F. Frantz
    Research
    Nature
    Volume: 591, P: 87-91

  • A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

    • Keren Carss
    • Bjarni V. Halldorsson
    • Ole Schulz-Trieglaff
    ResearchOpen Access
    Nature
    Volume: 645, P: 692-701

  • NanoSeq is used to detect mutations in single DNA molecules and analyses show that mutational processes that are independent of cell division are important contributors to somatic mutagenesis.

    • Federico Abascal
    • Luke M. R. Harvey
    • Iñigo Martincorena
    Research
    Nature
    Volume: 593, P: 405-410

  • The ancestry of the European bison (wisent) remains a mystery. Here, Cooper and colleagues examine ancient DNA from fossil remains of extinct bison, and reveal the wisent originated through the hybridization of the extinct Steppe bison and ancestors of modern cattle.

    • Julien Soubrier
    • Graham Gower
    • Alan Cooper
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-7

  • Radiocarbon dates, stable isotope data and DNA sequencing indicate an Elasmotheriinae/Rhinocerotinae split by the Eocene period, and the extinction of Elasmotherium sibiricum no later than 39,000 years ago, to which its specialized diet was probably a contributing factor.

    • Pavel Kosintsev
    • Kieren J. Mitchell
    • Adrian M. Lister
    Research
    Nature Ecology & Evolution
    Volume: 3, P: 31-38

  • Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterogeneity in metastases from different organs.

    • Roy Rabbie
    • Naser Ansari-Pour
    • David J. Adams
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Genome-wide association analysis of an improved telomere length score, calculated from quantitative PCR and whole-genome sequencing measurements in 462,666 individuals in the UK Biobank, identifies novel genes and variants underlying this trait.

    • Oliver S. Burren
    • Ryan S. Dhindsa
    • Slavé Petrovski
    ResearchOpen Access
    Nature Genetics
    Volume: 56, P: 1832-1840

  • A set of three papers in Nature reports a new proteomics resource from the UK Biobank and initial analysis of common and rare genetic variant associations with plasma protein levels.

    • Ryan S. Dhindsa
    • Oliver S. Burren
    • Slavé Petrovski
    ResearchOpen Access
    Nature
    Volume: 622, P: 339-347