Results from the SWOG S1011 and LEA trials show that extended pelvic lymph node dissection during radical cystectomy for muscle-invasive bladder cancer offers no survival benefit. Novel perioperative systemic therapies could lead to true survival improvement for patients with muscle-invasive bladder cancer undergoing radical surgery and have the potential to implement bladder-preserving strategies.
- Kilian M. Gust
- Shahrokh F. Shariat
