Nature Search

The genome sequence and structure of rice chromosome 1

Takuji Sasaki
Takashi Matsumoto
Takashi Gojobori
ResearchOpen Access21 Nov 2002
Nature

Volume: 420, P: 312-316
High-resolution analysis with novel cell-surface markers identifies routes to iPS cells

Cellular reprogramming is shown to occur in an ordered, stepwise manner, marked by changes in the cell-surface markers CD44, ICAM1 and Nanog–eGFP; molecular characterization of discrete subpopulations of partially reprogrammed cells shows that reprogramming is not simply the reversal of the normal development process.

James O’Malley
Stavroula Skylaki
Keisuke Kaji
Research02 Jun 2013
Nature

Volume: 499, P: 88-91
Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in mice

In vivo delivery of CRISPR-Cas9 holds promise for treating muscular dystrophy, however, AAV delivery is known to be immunogenic. Here, the authors show that LNP delivery of CRISPR-Cas9 enables repeated injections into skeletal muscle and leads to restored dystrophin expression in multiple muscle groups.

Eriya Kenjo
Hiroyuki Hozumi
Akitsu Hotta
ResearchOpen Access08 Dec 2021
Nature Communications

Volume: 12, P: 1-13
Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping

Expression of Cas9 and gRNA from viral vectors in vivo may cause off-target activity. Here the authors present NanoMEDIC, which uses nanovesicles to transiently deliver editing machinery to hard-to-transfect cells.

Peter Gee
Mandy S. Y. Lung
Akitsu Hotta
ResearchOpen Access13 Mar 2020
Nature Communications

Volume: 11, P: 1-18
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Embryonic Stem Cell Proliferation Stimulated By Altered Anabolic Metabolism From Glucose Transporter 2-Transported Glucosamine

Jin Hyuk Jung
Kumiko Iwabuchi
Mary R. Loeken
ResearchOpen Access17 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Low-intensity pulsed ultrasound therapy promotes recovery from stroke by enhancing angio-neurogenesis in mice in vivo

Sadamitsu Ichijo
Tomohiko Shindo
Hiroaki Shimokawa
ResearchOpen Access02 Mar 2021
Scientific Reports

Volume: 11, P: 1-11

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