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Showing 1–5 of 5 results

Advanced filters: Author: Kunishige Onuma Clear advanced filters

Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold

Hiroshi Horie
Ken Fukumitsu
Etsuro Hatano
ResearchOpen Access10 Feb 2026
Scientific Reports

P: 1-11
Intratumour oxidative hotspots provide a niche for cancer cell dissemination

Ueda et al. develop a sensor targeted to tumour cells that tracks extracellular H₂O₂. Tumour cells in H₂O₂ hotspots undergo partial epithelial–mesenchymal transition and migrate away from H₂O₂ hotspots. This is not seen in NRF2-hyperactivated tumours.

Yoshifumi Ueda
Shigeki Kiyonaka
Nobuaki Takahashi
Research21 Feb 2025
Nature Cell Biology

Volume: 27, P: 530-543
Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis

Here the authors demonstrate that de novo DNA methylation mediated by DNMT3B is regulated by nitric oxide (NO). They also isolate a unique modulator (DBIC) that inhibits S-nitrosylation of DNMT3B, which mitigates cell proliferation and tumorigenic conversion in vivo.

Kosaku Okuda
Kengo Nakahara
Takashi Uehara
ResearchOpen Access04 Feb 2023
Nature Communications

Volume: 14, P: 1-16
Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth

Mizuho Ishikawa
Mitsuhiko Osaki
Hideya Endo
Research11 Feb 2019
Oncogene

Volume: 38, P: 4715-4728
Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases

Yusuke Kanda
Mitsuhiko Osaki
Futoshi Okada
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-13