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Showing 1–2 of 2 results
Advanced filters: Author: Kyoo Heo Clear advanced filters

  • The authors identify AgcT as the glycosyltransferase required for synthesis of Bacteroides fragilis-derived α-galactosylceramides (BfaGCs), metabolites known to regulate natural killer T cells, and its structural homologue BgsB that synthesizes α-glycosyl diacylglycerols (aGDGs). They establish a functional link between the production of BfaGCs or aGDGs and the activity and development of natural killer T cells.

    • Ji-Sun Yoo
    • Da-Jung Jung
    • Sungwhan F. Oh
    Research
    Nature Microbiology
    Volume: 10, P: 2797-2807

  • Carbon sources can modulate biofilm formation and host colonization in Vibrio cholerae. Here, Heo et al. show that this process is mediated by a component of the PEP:carbohydrate phosphotransferase system (PTS), which regulates c-di-GMP hydrolysis by interacting with a c-di-GMP phosphodiesterase.

    • Kyoo Heo
    • Young-Ha Park
    • Yeong-Jae Seok
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10