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Showing 1–50 of 72 results

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Machine learning for risk stratification in the emergency department (MARS-ED): a randomized controlled trial

Here the authors report a randomized controlled trial showing that a previously developed artificial intelligence model estimates patient mortality risk as accurately as doctors and standard risk scores, but did not change clinical care decisions in the emergency department. This suggests that prediction accuracy alone does not necessarily translate into real-world clinical impact.

Paul M. E. L. van Dam
William P. T. M. van Doorn
Steven J. R. Meex
ResearchOpen Access01 Dec 2025
Nature Communications

Volume: 17, P: 1-8
Large-scale multi-site study shows no association between musical training and early auditory neural sound encoding

Widely cited studies have claimed that musical training is associated with enhanced neural encoding for sound at early stages of the auditory system. Results from this large-scale multisite study do not support this earlier claim.

Kelly L. Whiteford
Lucas S. Baltzell
Andrew J. Oxenham
ResearchOpen Access08 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Engineering vascular potassium transport increases yield and drought resilience of cassava

Zierer et al. engineered cassava to express a modified potassium channel that enhances sugar flow, improving the yield and drought resilience. This strategy offers a route to increase cassava productivity in tropical regions.

W. Zierer
M. Fritzler
L. Bellin
ResearchOpen Access17 Dec 2025
Nature Plants

Volume: 11, P: 2498-2510
Direct observation of alkali metal colloids in alkali halide crystals

L. W. HOBBS
A. E. HUGHES
G. CHASSAGNE
Research29 Nov 1974
Nature

Volume: 252, P: 383-385
Diversity of iron oxidizers in wetland soils revealed by novel 16S rRNA primers targeting Gallionella-related bacteria

Juanjuan Wang
Gerard Muyzer
Hendrikus J Laanbroek
Research19 Feb 2009
The ISME Journal

Volume: 3, P: 715-725
The aerodynamic diameter of branched chain-like aggregates

J. A. M. M. KOPS
J. F. V.D. VATE
G. DIBBETS
Research29 Nov 1974
Nature

Volume: 252, P: 385-387
Particle Involvement in Fatty Acid Synthesis in Liver and Yeast Systems

S. ABRAHAM
I. L. CHAIKOFF
HALINA DEN
Research30 Dec 1961
Nature

Volume: 192, P: 1287-1288
Evidence for early dispersal of domestic sheep into Central Asia

Archaeological and biomolecular investigations of ancient sheep remains from the site of Obishir V in southern Kyrgyzstan reveal that domestic livestock and Neolithic lifeways reached the heart of Central Asia by ca. 6,000 BCE, thousands of years earlier than previously recognized.

William T. T. Taylor
Mélanie Pruvost
Svetlana Shnaider
Research08 Apr 2021
Nature Human Behaviour

Volume: 5, P: 1169-1179
β-Adrenergic activation and memory for emotional events

Larry Cahill
Bruce Prins
James L. McGaugh
Research20 Oct 1994
Nature

Volume: 371, P: 702-704
Long-Term Effects of Treatment for Acute Lymphoblastic Leukemia with and without Cranial Irradiation on Growth and Puberty: A Comparative Study

A C S Hokken-Koelega
J W D Van Doorn
S L S Drop
Research01 Jun 1993
Pediatric Research

Volume: 33, P: 577-582
Localized excitations in a vertically vibrated granular layer

Paul B. Umbanhowar
Francisco Melo
Harry L. Swinney
Research29 Aug 1996
Nature

Volume: 382, P: 793-796
A second molecular form of D₂ dopamine receptor in rat and bovine caudate nucleus

Christopher L. Chio
Gerard F. Hess
Rita M. Huff
Research18 Jan 1990
Nature

Volume: 343, P: 266-269
Longitudinal analysis of neutralizing antibodies against SARS-CoV-1 and different SARS-CoV-2 strains in breakthrough and unvaccinated COVID-19 patients in Thailand (2021-2022)

Prapassorn Poolchanuan
Vichapon Tiacharoen
Alessandro Sette
ResearchOpen Access03 Jan 2026
Scientific Reports

Volume: 16, P: 1-15
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
The visual perception of long outdoor distances

J. Farley Norman
Jessica L. Lewis
Roseanna D. Peterson
ResearchOpen Access08 Feb 2024
Scientific Reports

Volume: 14, P: 1-8
Identification of human D lactate dehydrogenase deficiency

D-lactic acidosis typically occurs in the context of short bowel syndrome; excess D-lactate is produced by intestinal bacteria. Here, the authors identify two point mutations in the human lactate dehydrogenase D (LDHD) gene that cause enzymatic loss of function and are associated with elevated plasma D-lactate.

Glen R. Monroe
Albertien M. van Eerde
Judith J. Jans
ResearchOpen Access01 Apr 2019
Nature Communications

Volume: 10, P: 1-8
Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
Amendments and CorrectionsOpen Access08 Sept 2025
Nature Communications

Volume: 16, P: 1-2
Influenza virus infection history shapes antibody responses to influenza vaccination

Recent prior influenza A infection is associated with elevated hemagglutinin-inhibiting antibody responses and greater breadth of reactivity to influenza strains following vaccination, suggesting that infection history boosts vaccine responses.

Maria Auladell
Hoang Vu Mai Phuong
Annette Fox
Research17 Feb 2022
Nature Medicine

Volume: 28, P: 363-372
Tunable room-temperature single-photon emission at telecom wavelengths from sp³ defects in carbon nanotubes

Single-photon emission with 99% purity is generated from sp³ defects in carbon nanotubes (CNTs) by optical excitation at room temperature. By increasing the CNT diameter from 0.76 nm to 0.94 nm, the emission wavelength can be changed from 1,100 nm to 1,600 nm.

Xiaowei He
Nicolai F. Hartmann
Stephen K. Doorn
Research31 Jul 2017
Nature Photonics

Volume: 11, P: 577-582
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.

Manuel A. Ferreira
Eric R. Gamazon
Georgia Chenevix-Trench
ResearchOpen Access15 Apr 2019
Nature Communications

Volume: 10, P: 1-18
Ultralong single-wall carbon nanotubes

L. X. Zheng
M. J. O'Connell
Y. T. Zhu
Research12 Sept 2004
Nature Materials

Volume: 3, P: 673-676
Palaeogenomic analysis of black rat (Rattus rattus) reveals multiple European introductions associated with human economic history

‘Archaeogenetic analysis of black rat remains reveals that this species was introduced into temperate Europe twice, in the Roman and medieval periods. This population turnover was likely associated with multiple historical and environmental factors.’

He Yu
Alexandra Jamieson
David Orton
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-13
The added value of H₂ antagonists in premedication regimens during paclitaxel treatment

Juul M. Cox
Leni van Doorn
Roelof W. F. van Leeuwen
Research24 Mar 2021
British Journal of Cancer

Volume: 124, P: 1647-1652
A novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma

Remko Hersmus
Bertie HCGM de Leeuw
Leendert HJ Looijenga
Research10 Jun 2009
European Journal of Human Genetics

Volume: 17, P: 1642-1649
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

Matthew Law, Mark Iles and colleagues report the results of a large-scale genome-wide meta-analysis of cutaneous malignant melanoma. They confirm previously reported association signals and identify five new susceptibility loci, with associated variants mapping within putative melanocyte regulatory elements.

Matthew H Law
D Timothy Bishop
Mark M Iles
Research03 Aug 2015
Nature Genetics

Volume: 47, P: 987-995
Limited geographic distribution of the novel cyclovirus CyCV-VN

Le Van Tan
Menno D. de Jong
H. Rogier van Doorn
ResearchOpen Access05 Feb 2014
Scientific Reports

Volume: 4, P: 1-4
Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation

M. Ibrahim-Kosta
P. Suchon
P. E. Morange
ResearchOpen Access06 Mar 2019
Scientific Reports

Volume: 9, P: 1-7
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Melanocytic nevus count is associated with melanoma risk. In this study, a meta-analysis of 11 nevus GWAS studies identifies novel SNPs in KITLG and 9q32, and bivariate analysis with melanoma GWAS meta-analysis reveals that most nevus genes affect melanoma risk, while melanoma risk loci do not alter the nevus count.

David L. Duffy
Gu Zhu
Nicholas G. Martin
ResearchOpen Access14 Nov 2018
Nature Communications

Volume: 9, P: 1-10
Myeloid neoplasms associated with t(3;12)(q26.2;p13) are clinically aggressive, show myelodysplasia, and frequently harbor chromosome 7 abnormalities

Arash Ronaghy
Shimin Hu
Tariq Muzzafar
Research27 Oct 2020
Modern Pathology

Volume: 34, P: 300-313
Human papillomavirus infection and squamous cell carcinoma of the conjunctiva

C Ateenyi-Agaba
S Franceschi
E Weiderpass
ResearchOpen Access08 Dec 2009
British Journal of Cancer

Volume: 102, P: 262-267
Diagnosis and management of Guillain–Barré syndrome in ten steps

In this Consensus Statement, Leonhard et al. provide a globally applicable guideline for the diagnosis and management of Guillain–Barré syndrome, including information on early recognition of the disease, prediction of clinical course and outcome, and management of complications and sequelae.

Sonja E. Leonhard
Melissa R. Mandarakas
Bart C. Jacobs
ReviewsOpen Access20 Sept 2019
Nature Reviews Neurology

Volume: 15, P: 671-683
Computers in behavioural research

Event recording methods have evolved from stopwatches and checksheets, through chart recorders and dedicated electronic event recorders, to flexible systems based on off-the-shelf microcomputers.

L. P. J. J. Noldus
E. L. H. M. van de Loo
P. H. A. Timmers
Comments & Opinion26 Oct 1989
Nature

Volume: 341, P: 767-768
ETV6 mutations and loss in AML-M0

F P G Silva
B Morolli
M Giphart-Gassler
Correspondence28 Feb 2008
Leukemia

Volume: 22, P: 1639-1643
Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension

R. Tobal
J. Potjewijd
P. van Paassen
ResearchOpen Access04 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Global synergistic actions to improve brain health for human development

In this Perspective, Owolabi et al. propose strategies to improve brain health and address the growing global burden of neurological disorders. They present a new framework — the neurological quadrangle — which aims to provide equitable and effective surveillance, prevention, acute care and rehabilitation of neurological disorders globally.

Mayowa O. Owolabi
Matilde Leonardi
Franco Servadei
Reviews19 May 2023
Nature Reviews Neurology

Volume: 19, P: 371-383
Inter-device reproducibility of transcutaneous bilirubin meters

Alida J. Dam-Vervloet
Marlijn D. van Erk
Nienke Bosschaart
ResearchOpen Access12 Sept 2020
Pediatric Research

Volume: 89, P: 770-775
Temporal correlations between RBD-ACE2 blocking and binding antibodies to SARS-CoV-2 variants in CoronaVac-vaccinated individuals and their persistence in COVID-19 patients

Prapassorn Poolchanuan
Wasin Matsee
Alessandro Sette
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-17
A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours

F A L M Eskens
C H Mom
E G E de Vries
ResearchOpen Access20 Nov 2007
British Journal of Cancer

Volume: 98, P: 80-85
Identification of kinase inhibitors as potential host-directed therapies for intracellular bacteria

Robin H. G. A. van den Biggelaar
Kimberley V. Walburg
Anno Saris
ResearchOpen Access26 Jul 2024
Scientific Reports

Volume: 14, P: 1-16
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

David L. Duffy
Gu Zhu
Nicholas G. Martin
Amendments and CorrectionsOpen Access14 Jan 2019
Nature Communications

Volume: 10, P: 1-3
Efficacy of a nurse-led sexual rehabilitation intervention for women with gynaecological cancers receiving radiotherapy: results of a randomised trial

Isabelle Suvaal
Susanna B. Hummel
Moniek M. ter Kuile
ResearchOpen Access03 Jul 2024
British Journal of Cancer

Volume: 131, P: 808-819
The laboratory parameters-derived CoLab score as an indicator of the host response in ICU COVID-19 patients decreases over time: a prospective cohort study

Tom Schoenmakers
Mathie P. G. Leers
Andrea Peeters
ResearchOpen Access08 Apr 2024
Scientific Reports

Volume: 14, P: 1-9
High quality of SARS-CoV-2 molecular diagnostics in a diverse laboratory landscape through supported benchmark testing and External Quality Assessment

John Sluimer
Willem M. R. van den Akker
Adam Meijer
ResearchOpen Access16 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Permanent diffuse alopecia after haematopoietic stem cell transplantation in childhood

D Bresters
D C M Wanders
R van Doorn
Research20 Mar 2017
Bone Marrow Transplantation

Volume: 52, P: 984-988
Dietary sodium restriction prevents vascular endothelial growth factor inhibitor-induced hypertension

Leni van Doorn
Wesley J. Visser
Jorie Versmissen
Research10 Nov 2022
British Journal of Cancer

Volume: 128, P: 354-362
Eight years of experience with vismodegib for advanced and multiple basal cell carcinoma patients in the Netherlands: a retrospective cohort study

Babette J. A. Verkouteren
Marlies Wakkee
Klara Mosterd
ResearchOpen Access19 Jan 2021
British Journal of Cancer

Volume: 124, P: 1199-1206
Exposure to intrauterine inflammation and late-onset sepsis in very preterm infants

Marle B. van Doorn
J. Patrick van der Voorn
Douwe H. Visser
Research17 Mar 2021
Pediatric Research

Volume: 91, P: 230-234
Outcome of ovarian cancer after breast cancer in BRCA1 and BRCA2 mutation carriers

Leendert H Zaaijer
Helena C van Doorn
Mieke Kriege
ResearchOpen Access18 Oct 2016
British Journal of Cancer

Volume: 115, P: 1174-1178
Clinical practice guidelines for the diagnosis and surveillance of BAP1 tumour predisposition syndrome

Fiona Lalloo
Anju Kulkarni
Helen Hanson
ResearchOpen Access22 Aug 2023
European Journal of Human Genetics

Volume: 31, P: 1261-1269
Germline ATM variants predispose to melanoma: a joint analysis across the GenoMEL and MelaNostrum consortia

B. Dalmasso
L. Pastorino
P. Ghiorzo
ResearchOpen Access14 Jul 2021
Genetics in Medicine

Volume: 23, P: 2087-2095

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