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Showing 1–5 of 5 results
Advanced filters: Author: Lance C. Seefeldt Clear advanced filters

  • The reduction of dinitrogen to ammonia catalyzed by nitrogenase involves long-range conformational changes within the enzyme complex, however, direct biophysical evidence of communication between the Fe protein and the MoFe protein is lacking. Here, the authors combine millisecond time-resolved hydrogen-deuterium exchange mass spectrometry and normal mode analysis, revealing molecular-level insights into how the Fe protein alters the stability and dynamics of the MoFe protein near the active site in a nucleotide-dependent manner.

    • Monika Tokmina-Lukaszewska
    • Qi Huang
    • Brian Bothner
    ResearchOpen Access
    Communications Chemistry
    Volume: 6, P: 1-8

  • Space bioprocess engineering integrates synthetic biology and bioprocess engineering with the specific goal to support human life in long term space missions. In this Perspective, Berliner and colleagues describe a pathway towards the development and implementation of space bioprocessing technologies of the future.

    • Aaron J. Berliner
    • Isaac Lipsky
    • Adam P. Arkin
    ReviewsOpen Access
    Communications Engineering
    Volume: 1, P: 1-8