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Showing 1–12 of 12 results

Advanced filters: Author: Lea A. Harrington Clear advanced filters

Telomerase primer specificity and chromosome healing

Lea A. Harrington
Lea A. Harrington
Research03 Oct 1991
Nature

Volume: 353, P: 451-454
Mapping the genetic landscape across 14 psychiatric disorders

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders.

Andrew D. Grotzinger
Josefin Werme
Jordan W. Smoller
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 406-415
Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Genome-wide analyses identify 30 independent loci associated with obsessive–compulsive disorder, highlighting genetic overlap with other psychiatric disorders and implicating putative effector genes and cell types contributing to its etiology.

Nora I. Strom
Zachary F. Gerring
Manuel Mattheisen
ResearchOpen Access13 May 2025
Nature Genetics

Volume: 57, P: 1389-1401
A contextual genomic perspective on physical activity and its relationship to health, well being and illness

Genome-wide association meta-analyses of leisure, work and home-time physical activity (PA) from European, African and Latin American ancestries provide insights into the biology of PA and its relationship to health and diseases.

Marco Galimberti
Daniel F. Levey
Joel Gelernter
ResearchOpen Access21 Jul 2025
Nature Genetics

Volume: 57, P: 1860-1871
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Trouble upstream

Mutations in the promoter sequence of the gene encoding a component of the enzyme telomerase have been discovered in patients with melanoma, suggesting that mutations in this regulatory region can drive tumour development.

E. Elizabeth Patton
Lea Harrington
News & Views20 Mar 2013
Nature

Volume: 495, P: 320-321
GREGoR: accelerating genomics for rare diseases

The GREGoR consortium provides foundational resources and substrates for the future of rare disease genomics.

Moez Dawood
Ben Heavner
Gabrielle C. Villard
Reviews12 Nov 2025
Nature

Volume: 647, P: 331-342
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Does the reservoir for self-renewal stem from the ends?

Lea Harrington
Reviews20 Sept 2004
Oncogene

Volume: 23, P: 7283-7289
Telomere dysfunction: multiple paths to the same end

Lea Harrington
Murray O Robinson
Reviews11 Feb 2002
Oncogene

Volume: 21, P: 592-597
Mammographic density, blood telomere length and lipid peroxidation

Natalie J. Erdmann
Lea A. Harrington
Lisa J. Martin
ResearchOpen Access19 Jul 2017
Scientific Reports

Volume: 7, P: 1-9