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Advanced filters: Author: Leontine Sandforth Clear advanced filters

Prevention of type 2 diabetes through prediabetes remission without weight loss

A post hoc analysis of a multicentre, randomised trial showed that prediabetes remission is possible without total weight loss—providing weight is distributed to subcutaneous deposits as opposed to visceral ones.

Arvid Sandforth
Elsa Vazquez Arreola
Reiner Jumpertz von Schwartzenberg
ResearchOpen Access29 Sept 2025
Nature Medicine

Volume: 31, P: 3330-3340
The interplay of central insulin and menstrual cycle on functional brain networks and neural food cue reactivity in women

Central insulin effects on brain networks and food cue reactivity in the hippocampus and striatum vary dynamically across the menstrual cycle in premenopausal women, with estradiol and progesterone predicting these changes.

Julia Hummel
Sixiu Zhao
Stephanie Kullmann
ResearchOpen Access06 Jan 2026
Communications Biology

Volume: 9, P: 1-12
A short-term, high-caloric diet has prolonged effects on brain insulin action in men

Short-term overeating with calorie-rich snacks is shown to disrupt insulin action in the brain of men, which outlasted the time-frame of overeating.

Stephanie Kullmann
Lore Wagner
Andreas L. Birkenfeld
ResearchOpen Access21 Feb 2025
Nature Metabolism

Volume: 7, P: 469-477