Nature Search

Cholesterol-rich lysosomes induced by respiratory syncytial virus promote viral replication by blocking autophagy flux

RSV hijacks cholesterol or autophagy pathways to facilitate optimal replication. Here, the authors show that RSV-mediated changes in lysosomal cholesterol metabolism promote RSV-F accumulation in lysosomes by blocking autophagy flux, thereby facilitating viral replication.

Lifeng Chen
Jingjing Zhang
Zhong Liu
ResearchOpen Access26 Jul 2024
Nature Communications

Volume: 15, P: 1-18
Active control of magnetoresistance of organic spin valves using ferroelectricity

Organic materials potentially offer a low-cost, flexible and environment-friendly route to spintronics. Here, the authors demonstrate an organic spin-valve device in which an electric field can control both the magnitude and the sign of magnetoresistance.

Dali Sun
Mei Fang
Jian Shen
ResearchOpen Access10 Jul 2014
Nature Communications

Volume: 5, P: 1-6
Exploration of hanging coffin customs and the bo people in China through comparative genomics

Hanging Coffins were a mortuary tradition practiced in southern China and Southeast Asia. Here, the authors show that different groups of ancient Hanging Coffin practitioners are genetically related, and that they are ancestors of present-day Bo people.

Hui Zhou
Le Tao
Xiaoming Zhang
ResearchOpen Access20 Nov 2025
Nature Communications

Volume: 16, P: 1-13
Adaptive metal–organic frameworks with crystalline dynamicity for durable gas separation

A radical-mediated dynamic remedial strategy based on bio-inspired disulfide metathesis has been developed to construct metal–organic frameworks with crystalline dynamicity. The disulfide exchange-based crystal dynamics of the metal–organic frameworks allows for sustained gas separation.

Cheng-Xia Chen
Xili Cui
Cheng-Yong Su
Research24 Oct 2025
Nature Synthesis

Volume: 5, P: 129-138
Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development

Single-cell RNA-sequencing of seven mouse developmental stages identifies lineage-specific and shared regulatory programs controlling cell-fate decisions. Cross-species analysis associates differentiation potency with ribosomal protein gene expression.

Lijiang Fei
Haide Chen
Guoji Guo
Research11 Jul 2022
Nature Genetics

Volume: 54, P: 1051-1061
Reverse design of broadband sound absorption structure based on deep learning method

Yihong Zhou
Lifeng Ma
Zhiyuan Zhu
ResearchOpen Access14 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Nuclear receptor corepressor 1 deficiency exacerbates asthma by modulating macrophage polarization

Chenchen Hou
Lifeng Yan
Sheng-Zhong Duan
ResearchOpen Access29 Nov 2023
Cell Death Discovery

Volume: 9, P: 1-9
Exosomal novel-miRNA-126 mediates vascular endothelial dysfunction by targeting AhR-NLRP3 pathway in nonalcoholic steatohepatitis

Qiuhe Chen
Lifeng Ye
Yang Chen
ResearchOpen Access25 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Nutrition impact on ILC3 maintenance and function centers on a cell-intrinsic CD71–iron axis

Iron metabolism has been shown to play an important role in the development and function of the immune system, but its role in ILC3s is unclear. Here the authors show that CD71-mediated iron metabolism controls ILC3 proliferation and the host response to Citrobacter rodentium infection and CD71 expression is regulated by Ahr signaling.

Lifeng Xiong
Eric Y. Helm
Liang Zhou
Research14 Sept 2023
Nature Immunology

Volume: 24, P: 1671-1684
Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

In this study, authors identified neutralizing antibodies by isolating B cells from SARS-CoV-2 Delta infected patients and detect altered structural features, likely introduced by somatic hypermutation, that are involved in epitope binding and increase neutralization breadth against virus variants.

Haisheng Yu
Banghui Liu
Xiaoping Tang
ResearchOpen Access24 Feb 2023
Nature Communications

Volume: 14, P: 1-14
Photonic crystal enhanced fluorescence emission and blinking suppression for single quantum dot digital resolution biosensing

Nanoscale emitters are useful for measuring biomolecular interactions, but are limited by weak signals. Here, the authors use a photonic crystal surface for 3000-fold signal enhancement, achieving single emitter sensitivity with extended on-time, and demonstrate its application in miRNA biomarker sensing.

Yanyu Xiong
Qinglan Huang
Brian T. Cunningham
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Group 3 innate lymphoid cell pyroptosis represents a host defence mechanism against Salmonella infection

Salmonella promotes IL-22 production in group 3 innate lymphoid cells (ILC3s) to promote infection, and invades ILC3s causing caspase-1 activation and pyroptosis, which control bacterial replication.

Lifeng Xiong
Shifeng Wang
Liang Zhou
Research06 Jun 2022
Nature Microbiology

Volume: 7, P: 1087-1099
Mitochondrial transcription factor A in RORγt⁺ lymphocytes regulate small intestine homeostasis and metabolism

RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt⁺ lymphocyte homeostasis and metabolic control in a murine in vivo model.

Zheng Fu
Joseph W. Dean
Liang Zhou
ResearchOpen Access22 Jul 2021
Nature Communications

Volume: 12, P: 1-16
Stanniocalcin 2 governs cancer cell adaptation to nutrient insufficiency through alleviation of oxidative stress

Shuo Qie
Haijuan Xiong
Nianli Sang
ResearchOpen Access06 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-15
Author Correction: Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

Yongxia Zhu
Tinghong Ye
Yuquan Wei
Amendments and CorrectionsOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-3
ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia

Yiwei Xiong
Yanli Li
Hebin Liu
Research30 May 2022
Cellular & Molecular Immunology

Volume: 19, P: 898-912
Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

Yongxia Zhu
Tinghong Ye
Yuquan Wei
ResearchOpen Access02 Feb 2016
Scientific Reports

Volume: 6, P: 1-13

Search

Cholesterol-rich lysosomes induced by respiratory syncytial virus promote viral replication by blocking autophagy flux

Active control of magnetoresistance of organic spin valves using ferroelectricity

Exploration of hanging coffin customs and the bo people in China through comparative genomics

Adaptive metal–organic frameworks with crystalline dynamicity for durable gas separation

Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development

Reverse design of broadband sound absorption structure based on deep learning method

Nuclear receptor corepressor 1 deficiency exacerbates asthma by modulating macrophage polarization

Exosomal novel-miRNA-126 mediates vascular endothelial dysfunction by targeting AhR-NLRP3 pathway in nonalcoholic steatohepatitis

Nutrition impact on ILC3 maintenance and function centers on a cell-intrinsic CD71–iron axis

Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

Photonic crystal enhanced fluorescence emission and blinking suppression for single quantum dot digital resolution biosensing

Group 3 innate lymphoid cell pyroptosis represents a host defence mechanism against Salmonella infection

Mitochondrial transcription factor A in RORγt⁺ lymphocytes regulate small intestine homeostasis and metabolism

Stanniocalcin 2 governs cancer cell adaptation to nutrient insufficiency through alleviation of oxidative stress

Author Correction: Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia

Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

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