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Showing 1–4 of 4 results
Advanced filters: Author: Lihan Xie Clear advanced filters

  • Polyketide synthases are powerful assembly line enzymes for the production of organic compounds. Here, the authors develop a versatile engineering strategy for assembly line reprogramming, enabling custom biosynthesis of designer molecules.

    • Zilei Huang
    • Shengling Xie
    • Lihan Zhang
    Research
    Nature Chemical Biology
    Volume: 21, P: 1361-1367

  • Polyketide synthases are powerful multidomain enzymes for the synthesis of organic compounds. Here, the authors present a strategy to use the thioester reductase domain in polyketide synthases for the stereoselective and customizable production of non-natural alcohols.

    • Shunyu Yao
    • Shengling Xie
    • Lihan Zhang
    Research
    Nature Chemical Biology
    Volume: 21, P: 1368-1375

  • Observations indicating the chiral nature of superconducting states in five rhombohedral tetralayer and pentalayer graphene devices without moiré superlattice effects are reported, establishing a pure carbon material for the study of topological superconductivity.

    • Tonghang Han
    • Zhengguang Lu
    • Long Ju
    Research
    Nature
    Volume: 643, P: 654-661

  • A subpopulation of Caenorhabditis elegans, in which there is a naturally occurring transient increase in reactive oxygen species during early development, exhibits increased stress resistance, improved redox homeostasis and prolonged lifespan, which are linked to a global decrease in level of the histone mark H3K4me3.

    • Daphne Bazopoulou
    • Daniela Knoefler
    • Ursula Jakob
    Research
    Nature
    Volume: 576, P: 301-305