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Showing 1–2 of 2 results
Advanced filters: Author: Linghang Zeng Clear advanced filters

  • The role of lysine crotonylation (Kcr) in MASLD pathogenesis remains unclear. Here, the authors identify a PCAF/SIRT7-IDH1 Kcr axis that ameliorates hepatic steatosis by boosting TCA cycle activity, uncovering a new mechanism and therapeutic target for MASLD.

    • Shanshan Liu
    • Yu Ji
    • Zhongtao Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21

  • In this study, Chen and colleagues present genomic sequences of 102 SARS-CoV-2 isolates collected in Beijing. They look closely at genomic variation between isolates that arose as a result of domestic and global transmission. Their data suggest that SARS-CoV-2 genomes have a high mutational tolerance, which may have potential implications for the development of vaccines.

    • Pengcheng Du
    • Nan Ding
    • Chen Chen
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-9