The emergence of hematopoietic stem and progenitor cells is finely tuned by a variety of signaling pathways. Here, the authors find that Nlrc3 is highly expressed during hematopoietic differentiation in vivo and in vitro, activates the Notch pathway, and acts downstream of NF-kB signaling.
- Shuyang Cai
- Honghu Li
- He Huang