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Showing 1–2 of 2 results
Advanced filters: Author: Lisa M. Massoudi Clear advanced filters

  • A preclinical covalent compound, CMX410, contains a aryl fluorosulfate warhead that targets the acyltransferase domain of Mtb Pks13, an essential enzyme in cell-wall biosynthesis, making it a promising candidate for tuberculosis treatment regimens.

    • Inna V. Krieger
    • Paridhi Sukheja
    • Case W. McNamara
    Research
    Nature
    Volume: 645, P: 755-763