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Showing 1–11 of 11 results
Advanced filters: Author: Liuxiang Yang Clear advanced filters

  • Gastric Squamous Cell Carcinoma (GSCC) is a rare subtype of gastric cancer with unknown etiology. Here, the authors identify frequent mutations in epigenetic regulation genes including EZH2 in twenty GSCC patient samples, and demonstrate that EZH2 loss, along with TP53 and PTEN loss, leads to GSCC in mouse models.

    • Mengsha Zhang
    • Ailing Zhong
    • Chong Chen
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • The synthesis, recovery and detailed characterization of bulk hexagonal diamond under high pressure and temperature conditions using precursor graphite carbon is described, demonstrating the first successful synthesis in the 100 µm to millimetre size range.

    • Liuxiang Yang
    • Kah Chun Lau
    • Ho-kwang Mao
    Research
    Nature
    Volume: 644, P: 370-375

  • The nanostructured diamond capsule process with the inert gases solid argon and neon is demonstrated, where the trapped volatile gases could sustain their high-pressure states without confinement of conventional high-pressure vessels, opening up the possibility of in-depth investigations of high-pressure phenomena.

    • Zhidan Zeng
    • Jianguo Wen
    • Qiaoshi Zeng
    Research
    Nature
    Volume: 608, P: 513-517

  • Exploration of metastable phases of a given elemental composition is a data-intensive task. Here the authors integrate first-principles atomistic simulations with machine learning and high-performance computing to allow a rapid exploration of the metastable phases of carbon.

    • Srilok Srinivasan
    • Rohit Batra
    • Subramanian K.R.S. Sankaranarayanan
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Diamond’s properties are dictated by its crystalline, fully tetrahedrally bonded structure. Here authors synthesize a bulk sp 3-bonded amorphous form of carbon under high pressure and temperature, show that it has bulk modulus comparable to crystalline diamond and that it can be recovered under ambient conditions.

    • Zhidan Zeng
    • Liuxiang Yang
    • Ho-kwang Mao
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • Iron oxides prevail in the deep Earth, at extreme pressures and temperatures, with different stoichiometries than in ambient conditions. Here, high-pressure synchrotron X-ray spectroscopic measurements reveal the oxidation states of Fe and O in iron superoxide, shedding light on the puzzling chemistry of iron and oxygen in the deep Earth

    • Jin Liu
    • Qingyang Hu
    • Wendy L. Mao
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-8

  • Calcium and oxygen are abundant elements in the Earth’s mantle, largely present as calcium oxide. Here the authors show, by experiments and computations, that calcium ozonide (CaO3) is stabilized at the high pressures and temperatures characteristic of the lower mantle, with implications for the deep Earth’s chemistry.

    • Yanchao Wang
    • Meiling Xu
    • Yanming Ma
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-7

  • First-principles calculations and experiments are used to identify a stable, pyrite-structured iron oxide at 76 gigapascals and 1,800 kelvin that holds an excessive amount of oxygen and to show that goethite (rust) decomposes under these deep lower-mantle conditions to form an iron oxide and release hydrogen; this process provides another way to interpret the origin of seismic and geochemical anomalies in the deep lower mantle of Earth.

    • Qingyang Hu
    • Duck Young Kim
    • Ho-Kwang Mao
    Research
    Nature
    Volume: 534, P: 241-244