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Showing 1–15 of 15 results
Advanced filters: Author: Louis Ngai Clear advanced filters

  • Circadian oscillation of gene expression controls gut tissue homeostasis. The transcription factors REV-ERBα and REV-ERBβ, which control the expression of clock genes, are also central to maintaining innate lymphoid cells in a state that facilitates the maintenance of a balanced and healthy intestine.

    • Siu Ling Tai
    • Louis Ngai
    • Arthur Mortha
    News & Views
    Nature Immunology
    Volume: 26, P: 1428-1429

  • A preprint by Kaltenbach et al. shows a role for cytoskeletal control mechanisms in contributing to the tissue maintenance of mast cells.

    • Louis Ngai
    • Arthur Mortha
    Research Highlights
    Nature Reviews Immunology
    Volume: 24, P: 541

  • The BRAIN Initiative Cell Census Network has constructed a multimodal cell census and atlas of the mammalian primary motor cortex in a landmark effort towards understanding brain cell-type diversity, neural circuit organization and brain function.

    • Edward M. Callaway
    • Hong-Wei Dong
    • Susan Sunkin
    ResearchOpen Access
    Nature
    Volume: 598, P: 86-102

  • Ley, Gordon and colleagues have analysed and compared published sequences of bacterial communities from humans with both free-living communities and those that are associated with diverse animals. They conclude that gut-associated microbiotas are profoundly different from other free-living microbiotas, and call for widespread sampling of the human gut microbiota to study how different cultures, lifestyles and technologies are impacting on the biodiversity within these fascinating communities.

    • Ruth E. Ley
    • Catherine A. Lozupone
    • Jeffrey I. Gordon
    Research
    Nature Reviews Microbiology
    Volume: 6, P: 776-788

  • With a comprehensive analysis of sequencing data, DNA copy number, gene expression and DNA methylation in a large number of human glioblastomas, The Cancer Genome Atlas project initiative provides a broad overview of the genes and pathways that are altered in this cancer type.

    • Roger McLendon
    • Allan Friedman
    • Elizabeth Thomson
    Research
    Nature
    Volume: 455, P: 1061-1068

  • In this Opinion article the authors propose that peptidoglycan is not only an essential structural component of the bacterial cell wall, but is also involved in diverse biological processes, such as microbial pathogenesis, symbiotic associations and a range of interactions between bacteria and other organisms.

    • Karen A. Cloud-Hansen
    • S. Brook Peterson
    • Jo Handelsman
    Reviews
    Nature Reviews Microbiology
    Volume: 4, P: 710-716

  • The mammalian intestine is colonized by complex indigenous bacterial communities that establish beneficial symbiotic relationships with their host, making important contributions to host metabolism and digestive efficiency. In this Opinion article, Lora Hooper explores the roles of immune suppression, evasion and subversion in the establishment of these important symbiotic relationships.

    • Lora V. Hooper
    Reviews
    Nature Reviews Microbiology
    Volume: 7, P: 367-374