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Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust
Xueyong Wang
Brian K. Kaspar
Amendments and Corrections06 Oct 2022
Nature Biotechnology

Volume: 40, P: 1692
RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Spinal muscular atrophy is an autosomal recessive disease of motor neurons caused by lack of the SMN gene. Foust et al. achieve long-term correction of the disease phenotype in a mouse model by intravenous delivery of SMN using the viral vector scAAV9.

Kevin D Foust
Xueyong Wang
Brian K Kaspar
Research28 Feb 2010
Nature Biotechnology

Volume: 28, P: 271-274
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia

Starczynowski and colleagues show that overexpression of TRAF6 in HSCs induces ubiquitination of the RNA-binding protein hnRNPA1 and alternative splicing of Arhgap1, which accounts for the hematopoietic defects in myelodysplastic syndromes.

Jing Fang
Lyndsey C Bolanos
Daniel T Starczynowski
Research26 Dec 2016
Nature Immunology

Volume: 18, P: 236-245
Ingestible hydrogel microparticles improve bee health after pesticide exposure

Bees are important components of sustainable agriculture through their pollination services, however, they are susceptible to pesticide toxicity. This study presents an ingestible hydrogel microparticle technology that can lessen the detrimental effects of toxicity from the imidacloprid pesticide.

Julia S. Caserto
Lyndsey Wright
Minglin Ma
Research05 Sept 2024
Nature Sustainability

Volume: 7, P: 1441-1451
Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

THOC2 is an essential subunit of Transcription mRNA Export complex of eukaryotic cells and its compromise causes adverse (neuro)development. Using mouse model and patient cells the authors unravel molecular pathology of the syndrome, from R-loops dysregulation, to altered transcriptome and DNA damage triggered cell death.

Rudrarup Bhattacharjee
Lachlan A. Jolly
Jozef Gecz
ResearchOpen Access08 Feb 2024
Nature Communications

Volume: 15, P: 1-25
Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Class I histone deacetylase complexes can be activated by inositol phosphates. Here, the authors investigate the stereochemical requirements for activation; use the crystal structure to understand substrate recognition, and suggest an entropically driven mechanism of allostery.

Peter J. Watson
Christopher J. Millard
John W. R. Schwabe
ResearchOpen Access25 Apr 2016
Nature Communications

Volume: 7, P: 1-13
Liquid crystals of neat boron nitride nanotubes and their assembly into ordered macroscopic materials

Boron nitride nanotubes (BNNTS) have only been shown to dissolve in chlorosulfonic acid (CSA) at low concentrations. Here the authors successfully demonstrate the formation of liquid crystals of BNNTs in CSA that can be used to produce macroscopically aligned neat fibers of BNNTs.

Cedric J. Simonsen Ginestra
Cecilia Martínez-Jiménez
Matteo Pasquali
ResearchOpen Access07 Jun 2022
Nature Communications

Volume: 13, P: 1-8
Body mass index and use and costs of primary care services among women aged 55–79 years in England: a cohort and linked data study

Seamus Kent
Susan A Jebb
Cathie Sudlow
ResearchOpen Access19 Dec 2018
International Journal of Obesity

Volume: 43, P: 1839-1848

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Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia

Ingestible hydrogel microparticles improve bee health after pesticide exposure

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Liquid crystals of neat boron nitride nanotubes and their assembly into ordered macroscopic materials

Body mass index and use and costs of primary care services among women aged 55–79 years in England: a cohort and linked data study

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