Latent HIV-1 reservoirs, in which the viral genome becomes permanently integrated into the host chromosome, are established early during primary infection and pose a substantial obstacle to the eradication of HIV-1 infection. Here, José Alcamí and colleagues discuss the mechanisms that are associated with HIV-1 latency and outline strategies for targeting HIV-1 reservoirs.
- Mayte Coiras
- María Rosa López-Huertas
- José Alcamí
