Nature Search

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Ryan D. Morin
Maria Mendez-Lago
Marco A. Marra
ResearchOpen Access27 Jul 2011
Nature

Volume: 476, P: 298-303
Activity of a trinuclear platinum complex in human ovarian cancer cell lines sensitive and resistant to cisplatin: cytotoxicity and induction and gene-specific repair of DNA lesions

G Colella
M Pennati
N Zaffaroni
ResearchOpen Access15 May 2001
British Journal of Cancer

Volume: 84, P: 1387-1390
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

Analysis of 1,988 cases of B-cell acute lymphoblastic leukemia characterizes 23 subtypes defined by genomic features and shows that two of the subtypes have frequent PAX5 alterations.

Zhaohui Gu
Michelle L. Churchman
Charles G. Mullighan
Research14 Jan 2019
Nature Genetics

Volume: 51, P: 296-307
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

Susan Slager and colleagues report a meta-analysis of genome-wide association studies for chronic lymphocytic leukemia (CLL). They identify nine loci newly associated with CLL.

Sonja I Berndt
Christine F Skibola
Susan L Slager
Research16 Jun 2013
Nature Genetics

Volume: 45, P: 868-876
Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma

Christine Skibola and colleagues report a genome-wide association study for three subtypes of non-Hodgkin lymphoma. They report an association of a variant in the PSORS1 region in the MHC to increased risk of follicular lymphoma.

Christine F Skibola
Paige M Bracci
Kevin M Brown
Research20 Jul 2009
Nature Genetics

Volume: 41, P: 873-875
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

Group 2 innate lymphoid cells (ILC2s) modulate inflammatory and allergic responses, but their function in cancer immunity is still unclear. Here the authors show that, in acute promyelocytic leukaemia, tumour-activated ILC2s secrete IL-13 to induce myeloid-derived suppressor cells and support tumour growth.

Sara Trabanelli
Mathieu F. Chevalier
Camilla Jandus
ResearchOpen Access19 Sept 2017
Nature Communications

Volume: 8, P: 1-14
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping

Lane, Simon, Vintu et al. analyze the protein content of small extracellular vesicles produced by different glioblastoma cell lines and patient-derived stem cells. They show that the proteomic cargo of small extracellular vesicles can be used as biomarkers for glioblastoma subtyping.

Rosemary Lane
Thomas Simon
Georgios Giamas
ResearchOpen Access19 Aug 2019
Communications Biology

Volume: 2, P: 1-12
Prophylaxis and treatment of chemo- and radiotherapy-induced oral mucositis – are there new strategies?

M Karthaus
C Rosenthal
A Ganser
Research10 Nov 1999
Bone Marrow Transplantation

Volume: 24, P: 1095-1108
Monitoring of neurogenic bladder management from hospital admission until discharge in spinal cord injury units: the SIRCA study

Ángel Gil-Agudo
Francisco Gutiérrez Henares
Michele Spinelli
ResearchOpen Access17 Sept 2025
Spinal Cord

Volume: 63, P: 530-537
Identification of key sequence features required for microRNA biogenesis in plants

The secondary structure of miRNA precursor sequences is known to affect processing by DICER-like proteins. Here Rojas et al. show that additional sequence features also play a regulatory role in plants with nucleotide identity at unpaired positions substantially impacting processing efficiency.

Arantxa M. L. Rojas
Salvador I. Drusin
Javier F. Palatnik
ResearchOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1-11
Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study

R P Gallagher
J M Elwood
J J Spinelli
Research01 Dec 1985
British Journal of Cancer

Volume: 52, P: 901-907
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Genome-wide analysis identifies 32 loci associated with breast cancer susceptibility, accounting for estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 status and tumor grade.

Haoyu Zhang
Thomas U. Ahearn
Montserrat García-Closas
Research18 May 2020
Nature Genetics

Volume: 52, P: 572-581
Urodynamic assessment during intravesical infusion of capsaicin for the treatment of refractory detrusor hyperreflexia

M Lazzeri
M Spinelli
D Turini
Research15 Jun 1999
Spinal Cord

Volume: 37, P: 440-443
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia

Carlo Gambacorti-Passerini and colleagues identify recurrent SETBP1 mutations in atypical chronic myeloid leukemia. The mutations, which cluster in a small region of SETBP1, are associated with high white blood cell counts and poor prognosis.

Rocco Piazza
Simona Valletta
Carlo Gambacorti-Passerini
Research09 Dec 2012
Nature Genetics

Volume: 45, P: 18-24
Dihydroxyacetone phosphate signals glucose availability to mTORC1

Levels of the glycolytic intermediate metabolite dihydroxyacetone phosphate are shown to signal cellular glucose availability to the mTORC1 complex through an AMPK-independent route.

Jose M. Orozco
Patrycja A. Krawczyk
David M. Sabatini
Research27 Jul 2020
Nature Metabolism

Volume: 2, P: 893-901
Second primary cancers of the breast: Incidence and risk factors

T G Hislop
J M Elwood
L G Ellison
Research01 Jan 1984
British Journal of Cancer

Volume: 49, P: 79-85
Motor phenotype is not associated with vascular dysfunction in symptomatic Huntington’s disease transgenic R6/2 (160 CAG) mice

A. Di Pardo
A. Carrizzo
C. Vecchione
ResearchOpen Access17 Feb 2017
Scientific Reports

Volume: 7, P: 1-9
Allergies and agricultural exposure as risk factors for multiple myeloma

R P Gallagher
J J Spinelli
D H Skippen
Research01 Dec 1983
British Journal of Cancer

Volume: 48, P: 853-857
31 Study in infants of low socio-economical level fed with artificial milk

B J Schmidt
M E Z Maluf
I A Oliveira
Research01 Feb 1981
Pediatric Research

Volume: 15, P: 181
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Roger Milne and colleagues conduct a genome-wide association study for estrogen receptor (ER)-negative breast cancer combined with BRCA1 mutation carriers in a large cohort. They identify ten new risk variants and find high genetic correlation between breast cancer risk for BRCA1 mutation carriers and risk of ER-negative breast cancer in the general population.

Roger L Milne
Karoline B Kuchenbaecker
Jacques Simard
Research23 Oct 2017
Nature Genetics

Volume: 49, P: 1767-1778
Association analysis identifies 65 new breast cancer risk loci

Association analysis identifies 65 new breast cancer risk loci, predicts target genes for known risk loci and demonstrates a strong overlap with somatic driver genes in breast tumours.

Kyriaki Michailidou
Sara Lindström
Douglas F. Easton
Research23 Oct 2017
Nature

Volume: 551, P: 92-94
Wearable microfluidic biosensors with haptic feedback for continuous monitoring of hydration biomarkers in workers

Julia C. Spinelli
Brandon J. Suleski
Alexander J. Aranyosi
ResearchOpen Access01 Feb 2025
npj Digital Medicine

Volume: 8, P: 1-12
Combination of US hyperthermia and radiotherapy on a preclinical glioblastoma model

Gianni Durando
Federica Vurro
Antonello E. Spinelli
ResearchOpen Access27 Aug 2024
Scientific Reports

Volume: 14, P: 1-9
Cis dichlorodiammine platinum induced DNA interstrand cross-links in primary cultures of human ovarian cancer

G Balconi
Y Pang
L Redaelli
Research01 Aug 1991
British Journal of Cancer

Volume: 64, P: 288-292
Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program

J Gabert
E Beillard
J J M van Dongen
Research09 Oct 2003
Leukemia

Volume: 17, P: 2318-2357
Author Correction: The REACH radiometer for detecting the 21-cm hydrogen signal from redshift z ≈ 7.5–28

E. de Lera Acedo
D. I. L. de Villiers
K. Zarb-Adami
Amendments and Corrections03 Oct 2022
Nature Astronomy

Volume: 6, P: 1332
Nitrogen isotopic composition as a gauge of tumor cell anabolism-to-catabolism ratio

Marietta Straub
Alexandra Auderset
Alfredo Martínez-García
ResearchOpen Access13 Nov 2023
Scientific Reports

Volume: 13, P: 1-9
Sacral neuromodulation for urinary retention

Sacral neuromodulation (SNM) has been investigated as a treatment for a range of refractory lower urinary tract disorders. In this Review, Kessler and Fowler discuss developments in SNM techniques and technology, assess patient outcomes, and consider potential mechanisms of action for this therapy.

Thomas M Kessler
Clare J Fowler
Reviews11 Nov 2008
Nature Clinical Practice Urology

Volume: 5, P: 657-666
Assessment of network module identification across complex diseases

In this DREAM challenge, 75 methods for the identification of disease-relevant modules from molecular networks are compared and validated with GWAS data. The authors provide practical guidelines for users and establish benchmarks for network analysis.

Sarvenaz Choobdar
Mehmet E. Ahsen
Daniel Marbach
ResearchOpen Access30 Aug 2019
Nature Methods

Volume: 16, P: 843-852
Successful pregnancy following very high-dose total body irradiation (1575 cGy) and bone marrow transplantation in a woman with acute myeloid leukemia

W-S Wang
C-H Tzeng
P-M Chen
Research06 Mar 1998
Bone Marrow Transplantation

Volume: 21, P: 415-417
310 Towards Elimination of Vertical Transmission of Hiv in SãO Paulo State, Brazil - Analysis of the Period 1984-2008

L H Matida
Ramos A N Junior
N Hearst
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 159
Effect of rehydration on guaiac-based faecal occult blood testing in colorectal cancer screening

G Castiglione
M Biagini
S Ciatto
Research01 May 1993
British Journal of Cancer

Volume: 67, P: 1142-1144
32 VARIABLES RELATED TO WORK OF THE FATHER INFLUENCING THE RATE OF INFANT SEVERE MALNUTRITION

M L Alvarez
F Wurgaft
E Largo
Research01 Feb 1981
Pediatric Research

Volume: 15, P: 181
A limit on the variation of the speed of light arising from quantum gravity effects

Lorentz invariance — the postulate that all observers measure exactly the same speed of light in vacuum, independent of photon energy — is a cornerstone of Einstein's special relativity, but it has been suggested that it might break near the Planck scale. A possible variation of photon speed with energy is a key test for this proposed violation; here, by studying sharp features in γ-ray burst light-curves to look for even tiny variations in photon speed, no evidence for the violation of Lorentz invariance is found.

A. A. Abdo
M. Ackermann
M. Ziegler
Research28 Oct 2009
Nature

Volume: 462, P: 331-334
HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium

A Cherubini
G L Taddei
A Arcangeli
ResearchOpen Access05 Dec 2000
British Journal of Cancer

Volume: 83, P: 1722-1729
1161 CHLAMYDIA-ASSOCIATED LOWER RESPIRATORY TRACT INFECTIONS (LRI) IN CHILDREN OVER 1 YEAR OF AGE

Ziad M Shehab
C George Ray
Lynn M Taussig
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 304
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

Post-transplantation relapse in acute myeloid leukemia patients without genomic loss of HLA is driven by transcriptional alterations in antigen presentation and T cell costimulation genes.

Cristina Toffalori
Laura Zito
Luca Vago
Research25 Mar 2019
Nature Medicine

Volume: 25, P: 603-611
Disease control in general practice patients with asthma

Hanneke A.H. Wijnhoven
Didi M.W. Kriegsman
Wim Stalman
Research01 Jun 2004
Primary Care Respiratory Journal

Volume: 13, P: 89-98
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

James Cerhan and colleagues report genome-wide association and meta-analysis studies to identify genetic susceptibility loci for diffuse large B cell lymphoma. They identify four loci that influence genetic susceptibility to this B cell malignancy.

James R Cerhan
Sonja I Berndt
Stephen J Chanock
Research28 Sept 2014
Nature Genetics

Volume: 46, P: 1233-1238
Neuromodulation for overactive bladder

Neuromodulation has emerged as a second-line treatment option for patients with overactive bladder (OAB) refractory to initial treatment. In this Review, the authors summarize the diagnosis and first-line treatment options for OAB before providing an in-depth discussion of neuromodulation.

Jamie Bartley
Jason Gilleran
Kenneth Peters
Reviews02 Jul 2013
Nature Reviews Urology

Volume: 10, P: 513-521
Self-starting harmonic frequency comb generation in a quantum cascade laser

Self-starting harmonic frequency comb generation with a THz repetition rate in a quantum cascade laser is demonstrated. The mode spacing uniformity is verified to within 5 × 10⁻¹² parts of the central frequency. The findings extend the range of applications of quantum cascade laser frequency combs.

Dmitry Kazakov
Marco Piccardo
Federico Capasso
Research16 Oct 2017
Nature Photonics

Volume: 11, P: 789-792
17β-Estradiol Differentially Regulates Stress Circuitry Activity in Healthy and Depressed Women

Emily G Jacobs
Laura M Holsen
Jill M Goldstein
Research12 Aug 2014
Neuropsychopharmacology

Volume: 40, P: 566-576
Malignant melanoma in relation to moles, pigmentation, and exposure to fluorescent and other lighting sources

J M Elwood
C Williamson
P J Stapleton
Research01 Jan 1986
British Journal of Cancer

Volume: 53, P: 65-74
Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Cantrell and colleagues perform a comparative quantitative mass spectrometric analysis of the proteomes of naïve and activated CD4⁺ and CD8⁺ T cells. Proteomes are dynamically regulated and mTORC1 inhibition leads to differential consequences depending on cell state.

Andrew J. M. Howden
Jens L. Hukelmann
Doreen A. Cantrell
Research07 Oct 2019
Nature Immunology

Volume: 20, P: 1542-1554
The effect of oestrogen and progesterone receptors on recurrence and survival in patients with carcinoma of the breast

J M Howat
M Harris
D M Barnes
Research01 Feb 1985
British Journal of Cancer

Volume: 51, P: 263-270
Tamoxifen metabolism: pharmacokinetic and in vitro study

MC Etienne
G Milano
M Namer
Research01 Jul 1989
British Journal of Cancer

Volume: 60, P: 30-35
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

Chand Khanna
Xiaolin Wan
Lee J Helman
Research04 Jan 2004
Nature Medicine

Volume: 10, P: 182-186
Molecular architecture of the chick vestibular hair bundle

In this Resource study, the authors used high-resolution mass spectrometry to elucidate the precise proteomic complement of the inner ear hair bundle. Many of the proteins that are enriched in the hair bundles are encoded by known deafness-associated genes.

Jung-Bum Shin
Jocelyn F Krey
Peter G Barr-Gillespie
Research20 Jan 2013
Nature Neuroscience

Volume: 16, P: 365-374
High-dose chemotherapy and autologous bone marrow transplant in relapsed Hodgkin's disease - a pragmatic prognostic index

MER O'Brien
S Milan
C Viner
Research01 May 1996
British Journal of Cancer

Volume: 73, P: 1272-1277

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