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Showing 101–150 of 289 results

Advanced filters: Author: M. Barbieri Clear advanced filters

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

Mark Caulfield, Paul Elliott and colleagues use data from the UK Biobank to perform genome-wide association analysis for blood pressure traits. They identify and validate 107 novel loci and highlight new biological pathways for potential therapeutic intervention for hypertension.

Helen R Warren
Evangelos Evangelou
Paul Elliott
Research30 Jan 2017
Nature Genetics

Volume: 49, P: 403-415
The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status

Anaplastic lymphoma kinase (ALK) inhibitors are currently being considered in neuroblastoma (NB), but its acquired resistance is reported in non-small cell lung cancers. Here, the authors have found PIM1 overexpression decreases sensitivity to ALK inhibitors in NB and combined ALK and PIM1 inhibition enhances anti-tumour efficacy in vitro and in PDX models.

Ricky M. Trigg
Liam C. Lee
Suzanne D. Turner
ResearchOpen Access28 Nov 2019
Nature Communications

Volume: 10, P: 1-13
Effect of hyperplasia and neoplasia on the activity and distribution of some dehydrogenases in the human thyroid gland

Heather A Ayre
R B Goudie
D M Goldberg
Research01 Jun 1968
British Journal of Cancer

Volume: 22, P: 205-219
Non-Gaussian models of diffusion weighted imaging for detection and characterization of prostate cancer: a systematic review and meta-analysis

V. Brancato
C. Cavaliere
S. Monti
ResearchOpen Access14 Nov 2019
Scientific Reports

Volume: 9, P: 1-15
Eight-hours conventional versus adaptive deep brain stimulation of the subthalamic nucleus in Parkinson’s disease

Tommaso Bocci
Marco Prenassi
Sara Marceglia
ResearchOpen Access28 Sept 2021
npj Parkinson's Disease

Volume: 7, P: 1-6
Complex multi-enhancer contacts captured by genome architecture mapping

A technique called genome architecture mapping (GAM) involves sequencing DNA from a large number of thin nuclear cryosections to develop a map of genome organization without the limitations of existing 3C-based methods.

Robert A. Beagrie
Antonio Scialdone
Ana Pombo
Research08 Mar 2017
Nature

Volume: 543, P: 519-524
A novel cryptic exon in intron 3 of the dystrophin gene was incorporated into dystrophin mRNA with a single nucleotide deletion in exon 5

R. Suminaga
Y. Takeshima
M. Matsuo
Research01 Apr 2002
Journal of Human Genetics

Volume: 47, P: 196-201
Effect of anthracycline analogs on photolabelling of p-glycoprotein by [¹²⁵I]iodomycin and [³H]azidopine: relation to lipophilicity and inhibition of daunorubicin transport in multidrug resistant cells

E Friche
EJF Demant
NI Nissen
Research01 Feb 1993
British Journal of Cancer

Volume: 67, P: 226-231
In vivo anti-tumour activity of FCE 23762, a methoxymorpholinyl derivative of doxorubicin active on doxorubicin-resistant tumour cells

M Ripamonti
G Pezzoni
M Grandi
Research01 May 1992
British Journal of Cancer

Volume: 65, P: 703-707
Quantitative PCR for leprosy diagnosis and monitoring in household contacts: A follow-up study, 2011–2018

Fernanda S. N. Manta
Raquel R. Barbieri
Milton O. Moraes
ResearchOpen Access13 Nov 2019
Scientific Reports

Volume: 9, P: 1-8
Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression

Drake and colleagues demonstrate that castration in prostate cancer models promotes IL-8 secretion and immunosuppressive myeloid-derived suppressor cell migration, and that inhibiting this axis in combination with checkpoint blockade can mitigate tumor progression.

Zoila A. Lopez-Bujanda
Michael C. Haffner
Charles G. Drake
Research19 Jul 2021
Nature Cancer

Volume: 2, P: 803-818
Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients

Paolo Poggio
Paola Songia
Maurizio Pesce
ResearchOpen Access22 Feb 2021
Scientific Reports

Volume: 11, P: 1-7
Mutation of Tec family kinases alters T helper cell differentiation

Edward M. Schaeffer
George S. Yap
Pamela L. Schwartzberg
Research12 Nov 2001
Nature Immunology

Volume: 2, P: 1183-1188
Cause and consequences of Common Snook (Centropomus undecimalis) space use specialization in a subtropical riverscape

Rolando O. Santos
Mack White
Jennifer S. Rehage
ResearchOpen Access15 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
A 2,000–year-old specimen with intraerythrocytic Bartonella quintana

R. Barbieri
B.-H.-A. Mai
M. Drancourt
ResearchOpen Access22 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
Correction: Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

Kathryn L. Lunetta
Felix R. Day
John R. B. Perry
Amendments and CorrectionsOpen Access17 Dec 2015
Nature Communications

Volume: 6, P: 1
EVALUATION OF A NEW TEST (PHADIATOP) FOR THE SCREENING OF RESPIRATORY ALLERGIC DISEASE IN CHILDREN

P Betti
M Ferrara
L Businco
Research01 Aug 1987
Pediatric Research

Volume: 22, P: 222
Artificial intelligence-enhanced echocardiography in cardiovascular disease management

In this Review, the authors explore the state of artificial intelligence (AI) applications in echocardiography, discussing the integration of AI throughout the echocardiographic workflow and highlighting the clinical implementation, challenges and future directions of AI-supported echocardiography.

Peder L. Myhre
Bjørnar Grenne
Carolyn S. P. Lam
Reviews05 Aug 2025
Nature Reviews Cardiology

Volume: 23, P: 164-182
Clonal evolution of chemotherapy-resistant urothelial carcinoma

Mark Rubin, Francesca Demichelis and colleagues study the evolution of urothelial carcinomas by performing whole-exome sequencing of tumors collected from patients before and after chemotherapy. They find marked within-patient tumor heterogeneity and increased mutations involved in integrin signaling pathways and APOBEC-induced mutation signatures after treatment.

Bishoy M Faltas
Davide Prandi
Mark A Rubin
Research17 Oct 2016
Nature Genetics

Volume: 48, P: 1490-1499
The pristine interior of comet 67P revealed by the combined Aswan outburst and cliff collapse

A bright outburst of activity from the nucleus of comet 67P, observed by Rosetta in July 2015, is traced back to a cliff that partially collapsed at the same time as the outburst, establishing a link between the two events. The collapse has also exposed the fresh ice present under the surface.

M. Pajola
S. Höfner
E. Baratti
Research21 Mar 2017
Nature Astronomy

Volume: 1, P: 1-8
Myeloperoxidase is not a good biomarker for preeclampsia prediction

L. Rocha-Penha
H. Bettiol
V. C. Sandrim
ResearchOpen Access31 Aug 2017
Scientific Reports

Volume: 7, P: 1-6
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

Levi Garraway and colleagues report exome sequencing of 112 prostate adenocarcinomas and matched normal tissues. They identify novel recurrent mutations in several genes, including MED12, FOXA1 and SPOP. They find that tumors harboring SPOP mutations lack the TMPRSS2-ERG fusion or other ETS rearrangements, supporting the hypothesis that SPOP mutation is an early driver event in prostate tumorigenesis.

Christopher E Barbieri
Sylvan C Baca
Levi A Garraway
Research20 May 2012
Nature Genetics

Volume: 44, P: 685-689
Adequate iodine nutrition in Sweden: a cross-sectional national study of urinary iodine concentration in school-age children

M Andersson
G Berg
E Nyström
Research10 Sept 2008
European Journal of Clinical Nutrition

Volume: 63, P: 828-834
Mutation analysis of the EGFR gene and downstream signalling pathway in histologic samples of malignant pleural mesothelioma

R Mezzapelle
U Miglio
R Boldorini
ResearchOpen Access04 Apr 2013
British Journal of Cancer

Volume: 108, P: 1743-1749
Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

V. Khachatryan
A.M. Sirunyan
E. Pesen
ResearchOpen Access13 May 2015
Nature

Volume: 522, P: 68-72
Publisher Correction: The tuatara genome reveals ancient features of amniote evolution

Neil J. Gemmell
Kim Rutherford
Haydn Edmonds
Amendments and CorrectionsOpen Access18 Aug 2020
Nature

Volume: 585, P: E3
Publisher Correction: The long tail of oncogenic drivers in prostate cancer

Joshua Armenia
Stephanie A. M. Wankowicz
Eliezer M. Van Allen
Amendments and Corrections31 May 2019
Nature Genetics

Volume: 51, P: 1194
Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer

K Kämpjärvi
N Mäkinen
P Vahteristo
ResearchOpen Access20 Sept 2012
British Journal of Cancer

Volume: 107, P: 1761-1765
Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly

Barbara F Akum
Maxine Chen
Bonnie L Firestein
Research18 Jan 2004
Nature Neuroscience

Volume: 7, P: 145-152
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

In this study, the authors show that NgR1 and NgR3 can act as functional receptors for chondroitin sulfate proteoglycans (CSPGs), mediating inhibition of axonal growth and regeneration. This suggests a convergent mechanism for CSPG- and myelin-associated inhibitor activities after axonal injury in the CNS.

Travis L Dickendesher
Katherine T Baldwin
Roman J Giger
Research11 Mar 2012
Nature Neuroscience

Volume: 15, P: 703-712
Human health implications of trace metal contamination in topsoils and brinjal fruits harvested from a famous brinjal-producing area in Bangladesh

Anika Bushra
H. M. Zakir
Supti Mallick
ResearchOpen Access22 Aug 2022
Scientific Reports

Volume: 12, P: 1-14
Coma morphology of comet 67P controlled by insolation over irregular nucleus

Images of 67P's nucleus from the Rosetta spacecraft, together with numerical simulations, show that the jet-like features of cometary comae can be produced by diffuse activity focused by the nucleus topography as well as non-uniform insolation over the surface.

X. Shi
X. Hu
J.-B. Vincent
Research21 May 2018
Nature Astronomy

Volume: 2, P: 562-567
Endometriosis

Endometriosis is a common inflammatory disease associated with pelvic pain and infertility and is characterized by the presence of tissue outside the uterus that resembles endometrium. This Primer describes the pathogenesis of the condition and the current outlook for future research.

Krina T. Zondervan
Christian M. Becker
Paola Viganò
Reviews19 Jul 2018
Nature Reviews Disease Primers

Volume: 4, P: 1-25
180 Long term pulmonary functional outcome of plasia (BPD) and, of premature birth (PB)

S Parat
C Moriette
C Caultier
Research01 Dec 1991
Pediatric Research

Volume: 30, P: 658
Entanglement and teleportation between polarization and wave-like encodings of an optical qubit

Interfacing quantum information between discrete and continuous would allow exploiting the best of both worlds, but it has been shown only for single-rail encoding. Here, the authors extend this to the more practical dual-rail encoding, realizing teleportation between a polarization qubit and a CV qubit.

Demid V. Sychev
Alexander E. Ulanov
A. I. Lvovsky
ResearchOpen Access10 Sept 2018
Nature Communications

Volume: 9, P: 1-7
Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells

D K Adigbli
D G G Wilson
M Loizidou
ResearchOpen Access31 Jul 2007
British Journal of Cancer

Volume: 97, P: 502-512
Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Valentina Iotchkova
Jie Huang
Nicole Soranzo
Amendments and Corrections02 Nov 2018
Nature Genetics

Volume: 50, P: 1752
A first update on mapping the human genetic architecture of COVID-19

Gita A. Pathak
Juha Karjalainen
J. Kenneth Baillie
ResearchOpen Access03 Aug 2022
Nature

Volume: 608, P: E1-E10
Early life dietary intervention in dairy calves results in a long-term reduction in methane emissions

S. J. Meale
M. Popova
D. P. Morgavi
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-13
Novel bacterial ADP-ribosylating toxins: structure and function

Bacterial ADP-ribosyltransferase toxins (bARTTs) transfer ADP-ribose to a range of eukaryotic proteins to promote bacterial pathogenesis. In this Review, the authors discuss the structural and functional properties of the most recently identified novel bARTTs, which are produced by various human, insect and plant pathogens and were identified using bioinformatic analyses.

Nathan C. Simon
Klaus Aktories
Joseph T. Barbieri
Reviews14 Jul 2014
Nature Reviews Microbiology

Volume: 12, P: 599-611
Two independent and primitive envelopes of the bilobate nucleus of comet 67P

The ‘onion-like’ stratification of the two lobes of the comet 67P/Churyumov–Gerasimenko reveals that its unusual shape is the result of a gentle collision merging two kilometre-sized objects in the early stages of the Solar System.

Matteo Massironi
Emanuele Simioni
Jean-Baptiste Vincent
Research28 Sept 2015
Nature

Volume: 526, P: 402-405
Large heterogeneities in comet 67P as revealed by active pits from sinkhole collapse

The size and spatial distribution of pits on comet 67P/Churyumov–Gerasimenko, which are active and probably created by a sinkhole process, imply that large heterogeneities exist in the physical, structural or compositional properties of the first few hundred metres below the current cometary surface.

Jean-Baptiste Vincent
Dennis Bodewits
Cecilia Tubiana
Research01 Jul 2015
Nature

Volume: 523, P: 63-66
Direct Expression of Bordetelia pertussis Toxin Subunits to High Levels in Escherichia coli

W. Neal Burnette
Vernon L. Mar
Jerry M. Keith
Research01 Jun 1988
Bio/Technology

Volume: 6, P: 699-706
Gene Replacement in Bordetella pertussis by Transformation with Linear DNA

G. R. Zealey
S. M. Loosmore
M. H. Klein
Research01 Nov 1990
Bio/Technology

Volume: 8, P: 1025-1029
The clinical activity of cyproterone acetate in advanced ovarian carcinoma. A London Gynaecology Oncology Group Study

P Thompson
P Wilson
R Leonard
Research01 Nov 1991
British Journal of Cancer

Volume: 64, P: 973-974
PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

Q Sun
L Ming
J Yu
Research04 May 2009
Oncogene

Volume: 28, P: 2348-2357
Expression of cyclins A and D and p21^(waf1/cip1) proteins in renal cell cancer and their relation to clinicopathological variables and patient survival

S Aaltomaa
P Lipponen
V-M Kosma
ResearchOpen Access30 Jul 1999
British Journal of Cancer

Volume: 80, P: 2001-2007
Ultrastructural Localisation Of Ricinus Communis-I Lectin To Skeletal Muscle From Foetuses At High Risk For Duchenne Muscular Dystrophy

T Voit
C A Sewry
V Dubowitz
Research01 Aug 1987
Pediatric Research

Volume: 22, P: 222
Role of Mdm4 in drug sensitivity of breast cancer cells

S Lam
K Lodder
A G Jochemsen
Research08 Feb 2010
Oncogene

Volume: 29, P: 2415-2426
Molecular determinants of Akt-induced keratinocyte transformation

C Segrelles
M Moral
J M Paramio
Research17 Oct 2005
Oncogene

Volume: 25, P: 1174-1185

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