Nature Search

Distinct genomic, microenvironmental, and nephron signatures in VHL kidney cysts and tumors

Isaline Rowe
Francesca Corea
Lucia Salerno
ResearchOpen Access09 Jan 2026
Scientific Reports

Volume: 16, P: 1-10
Smart parallel automated cryo-electron tomography

Smart parallel automated cryo-electron tomography (SPACEtomo) uses deep learning to fully automate data collection from lamella detection to tilt series acquisition, driving the future of cryo-ET through improved throughput and statistics.

Fabian Eisenstein
Yoshiyuki Fukuda
Radostin Danev
Research08 Aug 2024
Nature Methods

Volume: 21, P: 1612-1615
Cancer-specific survival after radical nephroureterectomy for upper urinary tract urothelial carcinoma: proposal and multi-institutional validation of a post-operative nomogram

D R Yates
V Hupertan
M Rouprêt
ResearchOpen Access28 Feb 2012
British Journal of Cancer

Volume: 106, P: 1083-1088
α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity

By using laser tweezers, the authors show that a single α-catenin molecule does not resist force on F-actin. However, clustering of multiple molecules and force applied toward F-actin pointed end engage a molecular switch in α-catenin, which unfolds and strongly binds F-actin.

C. Arbore
M. Sergides
M. Capitanio
ResearchOpen Access03 Mar 2022
Nature Communications

Volume: 13, P: 1-11
Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes

FluidFM-based force-controlled nanopipettes enable control of mechanical stimuli for the investigation of Piezo1-induced mechanosensation in cell membranes.

Ines Lüchtefeld
Igor V. Pivkin
Massimo Vassalli
ResearchOpen Access27 May 2024
Nature Methods

Volume: 21, P: 1063-1073
Dissecting myosin-5B mechanosensitivity and calcium regulation at the single molecule level

Myosin-5B is an actin-based motor important for endosome recycling, but the molecular mechanism underlying its motility remains unknown. Here authors use single molecule imaging and high-speed laser tweezers to dissect the mechanoenzymatic properties of myosin-5B, which shows processive motility with peculiar mechanosensitivity.

Lucia Gardini
Sarah M. Heissler
Marco Capitanio
ResearchOpen Access20 Jul 2018
Nature Communications

Volume: 9, P: 1-12
Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy

Licheva, Pflaum, Babic, Mancilla et al. show that low-affinity cargo–receptor interactions promote autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub and phagophore formation.

Mariya Licheva
Jeremy Pflaum
Claudine Kraft
ResearchOpen Access07 Jan 2025
Nature Cell Biology

Volume: 27, P: 283-297
Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models

In animal models, maternal obesity is associated with development of neurodevelopmental disorder like phenotypes. Here the authors show in a macaque model that in obese dams, cell-free fetal DNA methylation, inflammatory cytokines, and metabolites correlated with infant brain DNA methylation, lipids, and metabolites.

Benjamin I. Laufer
Yu Hasegawa
Janine M. LaSalle
ResearchOpen Access21 Sept 2022
Nature Communications

Volume: 13, P: 1-15
Polarized blazar X-rays imply particle acceleration in shocks

Polarization measurements are reported for the blazar Mk501, revealing a degree of X-ray polarization that is more than twice the optical value and supporting the shock-accelerated energy-stratified electron population scenario.

Ioannis Liodakis
Alan P. Marscher
Silvia Zane
ResearchOpen Access23 Nov 2022
Nature

Volume: 611, P: 677-681
A record of plume-induced plate rotation triggering subduction initiation

A mantle plume induced plate rotation that initiated subduction and rifting along a >12,000 km plate boundary about 105 Myr ago, according to an analysis of geological data and numerical simulations.

Douwe J. J. van Hinsbergen
Bernhard Steinberger
Wim Spakman
Research08 Jul 2021
Nature Geoscience

Volume: 14, P: 626-630
Discovery of X-ray polarization angle rotation in the jet from blazar Mrk 421

In June 2022, the IXPE satellite observed a shock passing through the jet of active galaxy Markarian 421. The rotation of the X-ray-polarized radiation over a 5-day period revealed that the jet contains a helical magnetic field.

Laura Di Gesu
Herman L. Marshall
Silvia Zane
Research17 Jul 2023
Nature Astronomy

Volume: 7, P: 1245-1258
Increasing AFM colloidal probe accuracy by optical tweezers

Tomasz Witko
Zbigniew Baster
Jakub Barbasz
ResearchOpen Access12 Jan 2021
Scientific Reports

Volume: 11, P: 1-10
Rheological inheritance controls the formation of segmented rifted margins in cratonic lithosphere

The evolution of rifts and rifted margins is controlled by the rheology of the lithosphere. Thus, pre-existing lateral rheological variations can dominate the rifting process and lead to margin segmentation, with along-strike changes in crustal structure and nature and timing of continental breakup.

M. Gouiza
J. Naliboff
ResearchOpen Access02 Aug 2021
Nature Communications

Volume: 12, P: 1-9
Unraveling weak and short South Asian wet season in the Early Eocene warmth

The Asian wet season in the Early Eocene was notably shorter and weaker compared to the present-day Asian summer monsoon, primarily attributed to the absence of the Tibetan highland as a heat source, according to DeepMIP-Eocene multi-model ensemble paleoclimate simulations.

S. Abhik
Fabio A. Capitanio
Sebastian Steinig
ResearchOpen Access16 Mar 2024
Communications Earth & Environment

Volume: 5, P: 1-12
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions

A multi-omics survey of progressive compared to regressive carcinoma in situ lesions provides a molecular map of early lung cancer development.

Vitor H. Teixeira
Christodoulos P. Pipinikas
Sam M. Janes
Research21 Jan 2019
Nature Medicine

Volume: 25, P: 517-525
Rhesus infant nervous temperament predicts peri-adolescent central amygdala metabolism & behavioral inhibition measured by a machine-learning approach

D. Holley
L. J. Campos
A. S. Fox
ResearchOpen Access15 Mar 2024
Translational Psychiatry

Volume: 14, P: 1-11
Clinical evaluation of seven tumour markers in lung cancer diagnosis: can any combination improve the results?

M Plebani
D Basso
A Cipriani
Research01 Jul 1995
British Journal of Cancer

Volume: 72, P: 170-173
c-erbB-2 oncoprotein detected by automated quantitative immunocytochemistry in breast carcinomas correlates with patients' overall and disease-free survival

C Charpin
S Garcia
L Andrac
Research01 Jun 1997
British Journal of Cancer

Volume: 75, P: 1667-1673
No intraindividual variation of disomy rate in sperm samples

A. Amiel
B. Bartoov
M. D. Fejgin
Research01 Oct 2002
Journal of Human Genetics

Volume: 47, P: 539-542
miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215

N M A White
H W Z Khella
G M Yousef
ResearchOpen Access27 Oct 2011
British Journal of Cancer

Volume: 105, P: 1741-1749
Highly inclined light sheet allows volumetric super-resolution imaging of efflux pumps distribution in bacterial biofilms

T. Vignolini
M. Capitanio
F. S. Pavone
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
Intermediate and low abundant protein analysis of vitamin D deficient obese and non-obese subjects by MALDI-profiling

Nasser M. Al-Daghri
Enrica Torretta
Cecilia Gelfi
ResearchOpen Access03 Oct 2017
Scientific Reports

Volume: 7, P: 1-10
Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

James T Winslow
Pamela L Noble
Thomas R Insel
Research19 Dec 2002
Neuropsychopharmacology

Volume: 28, P: 910-918
Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia

O Agid
B Shapira
B Lerer
Research17 Mar 1999
Molecular Psychiatry

Volume: 4, P: 163-172
Central Nervous System Monoamine Correlates of Social Dominance in Cynomolgus Monkeys (Macaca fascicularis)

Jay R Kaplan
Stephen B Manuck
J John Mann
Research27 Jul 2001
Neuropsychopharmacology

Volume: 26, P: 431-443
Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

Nasser M. Al-Daghri
Enrica Torretta
Cecilia Gelfi
ResearchOpen Access13 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
Long-term sexual outcomes after holmium laser enucleation of the prostate: which patients could benefit the most?

P Capogrosso
E Ventimiglia
A Salonia
Research28 Jul 2016
International Journal of Impotence Research

Volume: 28, P: 189-193
Ca²⁺-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak

Giovanni Quarato
Fabien Llambi
Douglas R. Green
Research20 Jun 2022
Cell Death & Differentiation

Volume: 29, P: 1318-1334
The Serotonin Reuptake Inhibitor Sertraline Reduces Excessive Alcohol Consumption in Nonhuman Primates: Effect of Stress

J Higley
M Hasert
M Linnoila
Research01 Jun 1998
Neuropsychopharmacology

Volume: 18, P: 431-443
Publisher Correction: Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

Nasser M. Al-Daghri
Enrica Torretta
Cecilia Gelfi
Amendments and CorrectionsOpen Access04 Feb 2020
Scientific Reports

Volume: 10, P: 1
Triglycerides and low HDL cholesterol predict coronary heart disease risk in patients with stable angina

Chiara Caselli
Raffaele De Caterina
Danilo Neglia
ResearchOpen Access20 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
MtDNA mutation associated with mitochondrial dysfunction in megakaryoblastic leukaemic cells

C Piccoli
M Ripoli
N Capitanio
Correspondence27 Mar 2008
Leukemia

Volume: 22, P: 1938-1941
Multidisciplinary studies on a sick-leader syndrome-associated mass stranding of sperm whales (Physeter macrocephalus) along the Adriatic coast of Italy

Sandro Mazzariol
Cinzia Centelleghe
Giovanni Di Guardo
ResearchOpen Access01 Aug 2018
Scientific Reports

Volume: 8, P: 1-18
Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

M D Bauman
A-M Iosif
D G Amaral
ResearchOpen Access09 Jul 2013
Translational Psychiatry

Volume: 3, P: e278

Search

Distinct genomic, microenvironmental, and nephron signatures in VHL kidney cysts and tumors

Smart parallel automated cryo-electron tomography

Cancer-specific survival after radical nephroureterectomy for upper urinary tract urothelial carcinoma: proposal and multi-institutional validation of a post-operative nomogram

α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity

Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes

Dissecting myosin-5B mechanosensitivity and calcium regulation at the single molecule level

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy

Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models

Polarized blazar X-rays imply particle acceleration in shocks

A record of plume-induced plate rotation triggering subduction initiation

Discovery of X-ray polarization angle rotation in the jet from blazar Mrk 421

Increasing AFM colloidal probe accuracy by optical tweezers

Rheological inheritance controls the formation of segmented rifted margins in cratonic lithosphere

Unraveling weak and short South Asian wet season in the Early Eocene warmth

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions

Rhesus infant nervous temperament predicts peri-adolescent central amygdala metabolism & behavioral inhibition measured by a machine-learning approach

Clinical evaluation of seven tumour markers in lung cancer diagnosis: can any combination improve the results?

c-erbB-2 oncoprotein detected by automated quantitative immunocytochemistry in breast carcinomas correlates with patients' overall and disease-free survival

No intraindividual variation of disomy rate in sperm samples

miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215

Highly inclined light sheet allows volumetric super-resolution imaging of efflux pumps distribution in bacterial biofilms

Intermediate and low abundant protein analysis of vitamin D deficient obese and non-obese subjects by MALDI-profiling

Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia

Central Nervous System Monoamine Correlates of Social Dominance in Cynomolgus Monkeys (Macaca fascicularis)

Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

Long-term sexual outcomes after holmium laser enucleation of the prostate: which patients could benefit the most?

Ca²⁺-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak

The Serotonin Reuptake Inhibitor Sertraline Reduces Excessive Alcohol Consumption in Nonhuman Primates: Effect of Stress

Publisher Correction: Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

Triglycerides and low HDL cholesterol predict coronary heart disease risk in patients with stable angina

MtDNA mutation associated with mitochondrial dysfunction in megakaryoblastic leukaemic cells

Multidisciplinary studies on a sick-leader syndrome-associated mass stranding of sperm whales (Physeter macrocephalus) along the Adriatic coast of Italy

Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

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