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Showing 101–150 of 735 results

Advanced filters: Author: M. Harada Clear advanced filters

Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease

Idiopathic multicentric Castleman disease (CD) is a rare and potentially fatal lymphoproliferative disorder. Authors here establish a mouse xenotransplantation model of the “not otherwise specified” subtype of the disease and show that the chemokine CXCL13 plays a pivotal role in the pathogenesis and likely produced by peripheral helper cells, which expand upon engraftment.

Takuya Harada
Yoshikane Kikushige
Kazuyuki Yoshizaki
ResearchOpen Access31 Oct 2023
Nature Communications

Volume: 14, P: 1-13
m⁶A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

Liu et al. show that reduced m⁶A mRNA methylation in endometrial cancer is oncogenic. Mechanistically, the AKT pathway is activated in these tumours due to altered expression of AKT regulators carrying m⁶A on their transcripts.

Jun Liu
Mark A. Eckert
Chuan He
Research27 Aug 2018
Nature Cell Biology

Volume: 20, P: 1074-1083
Nine novel single-nucleotide polymorphisms in the integrin β4 (ITGB4) gene in the Japanese population

A. Hirano
H. Nagai
M. Emi
Research01 Jan 2001
Journal of Human Genetics

Volume: 46, P: 35-37
Identification of parathyroid hormone-related protein-derived peptides immunogenic in human histocompatibility leukocyte antigen-A24⁺ prostate cancer patients

A Yao
M Harada
K Itoh
ResearchOpen Access15 Jun 2004
British Journal of Cancer

Volume: 91, P: 287-296
Growth history of hydrothermal black smoker chimneys

Rachel M. Haymon
Research24 Feb 1983
Nature

Volume: 301, P: 695-698
Tuberin activates the proapoptotic molecule BAD

A Freilinger
M Rosner
M Hengstschläger
Research15 May 2006
Oncogene

Volume: 25, P: 6467-6479
T_H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

Ahjoku Amadi-Obi
Cheng-Rong Yu
Charles E Egwuagu
Research13 May 2007
Nature Medicine

Volume: 13, P: 711-718
Observation of quantum entanglement with top quarks at the ATLAS detector

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s = 13 TeV and an integrated luminosity of 140 fb⁻¹.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access18 Sept 2024
Nature

Volume: 633, P: 542-547
Phosphoglucomutase polymorphism in an isolated community in Japan

Itsuro Nishigaki
Tohru Itoh
Motoharu Kondo
Research01 Dec 1978
Japanese Journal of Human Genetics

Volume: 23, P: 377-382
Identification of an S-antigen-like molecule in human choroid plexus and cerebrospinal fluid

H S Dua
Patricio F Reyes
Larry A Donoso
Research01 Nov 1992
Eye

Volume: 6, P: 594-598
Evaluation of choroidal melanin-containing tissue in healthy Japanese subjects by polarization-sensitive optical coherence tomography

Masahiro Miura
Shuichi Makita
Tatsuo Yamaguchi
ResearchOpen Access08 Mar 2022
Scientific Reports

Volume: 12, P: 1-9
Suppression of cell cycle progression by Jun dimerization protein (JDP2) involves down-regulation of cyclin A2

Jianzhi Pan
Koji Nakade
Kazunari Yokoyama
ResearchOpen Access08 Oct 2009
Nature Precedings

P: 1
Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells

K Aoki
M Aoki
M M Taketo
Research11 Dec 2006
Oncogene

Volume: 26, P: 3511-3520
Structure and function of human perforin

Mathias G. Lichtenheld
Kristin J. Olsen
Eckhard R. Podack
Research29 Sept 1988
Nature

Volume: 335, P: 448-451
A cross-sectional study on gut microbiota in prostate cancer patients with prostatectomy or androgen deprivation therapy

Joseph K. M. Li
Lynn L. Wang
Chi-Fai Ng
Research13 Apr 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 1063-1072
Butyrate prevents chemotherapy-induced gastrointestinal toxicity and microbial dysbiosis

Stanley M. Cheatham
Zayd Rehman
Hamid I. Akbarali
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 16, P: 1-17
A novel dimer configuration revealed by the crystal structure at 2.4 Å resolution of human interleukin-5

Michael V. Milburn
Anne M. Hassell
Timothy N. C. Wells
Research13 May 1993
Nature

Volume: 363, P: 172-176
Effect of assisted hatching on pregnancy outcomes following 1,678,872 single embryo transfers based on the Japan Assisted Reproductive Technology Registry

A. Kusamoto
M. Harada
Y. Hirota
ResearchOpen Access10 Dec 2025
Scientific Reports

Volume: 15, P: 1-10
A millisecond pulsar in a 32-minute binary orbit

J. G. Abies
D. McConnell
P. A. Hamilton
Research09 Nov 1989
Nature

Volume: 342, P: 158-161
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

P. H. St George-Hyslop
J. L. Haines
J. A. Hardy
Research13 Sept 1990
Nature

Volume: 347, P: 194-197
Evolution and advection of solar mesogranulation

Richard Muller
Hervé Auffret
Alan M. Title
Research26 Mar 1992
Nature

Volume: 356, P: 322-325
Lymphocyte activation by HIV-1 envelope glycoprotein

Hardy Kornfeld
William W. Cruikshank
David M. Center
Research29 Sept 1988
Nature

Volume: 335, P: 445-448
Molecular cloning, tissue expression, and chromosomal assignment of a novel gene encoding a subunit of the human signal-recognition particle

H. Harada
H. Nagai
M. Emi
Research01 Feb 2001
Journal of Human Genetics

Volume: 46, P: 70-75
RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation

M-C Kuo
D-C Liang
L-Y Shih
Research12 Mar 2009
Leukemia

Volume: 23, P: 1426-1431
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Measurements of acoustic correlation in the ocean with a high frequency echo-sounder

D. M. Farmer
G. B. Crawford
Research24 Feb 1983
Nature

Volume: 301, P: 698-700
Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

J. C. Smith
B. M. J. Price
D. Huylebroeck
Research21 Jun 1990
Nature

Volume: 345, P: 729-731
A planet orbiting the neutron star PSR1829–10

M. Bailes
A. G. Lyne
S. L. Shemar
Research25 Jul 1991
Nature

Volume: 352, P: 311-313
Self-assembling organic nanotubes based on a cyclic peptide architecture

M. Reza Ghadiri
Juan R. Granja
Nina Khazanovich
Research25 Dec 1993
Nature

Volume: 366, P: 324-327
Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes: genomic structure and seven polymorphisms of the FAP-1 gene

S. Yoshida
H. Harada
M. Emi
Research01 Nov 2002
Journal of Human Genetics

Volume: 47, P: 614-619
Intragenic viral silencer element regulates HTLV-1 latency via RUNX complex recruitment

An intragenic open chromatin region in human T cell leukaemia virus type 1 functions as a transcriptional silencer and regulates transcriptional burst by recruiting the host transcription factor RUNX.

Kenji Sugata
Akhinur Rahman
Yorifumi Satou
ResearchOpen Access13 May 2025
Nature Microbiology

Volume: 10, P: 1447-1462
A potential catalytic site revealed by the 1.7-Å crystal structure of the amino-terminal signalling domain of Sonic hedgehog

Traci M. Tanaka Hall
Jeffery A. Porter
Daniel J. Leahy
Research09 Nov 1995
Nature

Volume: 378, P: 212-216
An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies

David J. Evans
Jane McKeating
Jeffrey W. Almond
Research01 Jun 1989
Nature

Volume: 339, P: 385-388
IUE observations of the hot components in two symbiotic stars

A. G. Michalitsianos
M. Kafatos
S. P. Maran
Research13 Mar 1980
Nature

Volume: 284, P: 148-150
Record of fluid–rock interactions on Mars from the meteorite ALH84001

C. S. Romanek
M. M. Grady
E. K. Gibson Jr
Research15 Dec 1994
Nature

Volume: 372, P: 655-657
Path of magnetic flux lines through high-T_c copper oxide superconductors

Zhen Yao
Seokwon Yoon
Charles M. Lieber
Research27 Oct 1994
Nature

Volume: 371, P: 777-779
Localization of a breast cancer tumour-suppressor gene to a 3-cM interval within chromosomal region 16q22

A Iida
R Isobe
M Emi
Research01 Jan 1997
British Journal of Cancer

Volume: 75, P: 264-267
Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes

H B Fleisig
N I Orazio
L Nagarajan
Research19 Feb 2007
Oncogene

Volume: 26, P: 4797-4805
Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

Fotini Gounari
Sabina Signoretti
Khashayarsha Khazaie
Research05 Jun 2002
Oncogene

Volume: 21, P: 4099-4107
The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity

Blood vessel integrity is critical to maintain brain health. Here, the authors show that both the liver and the muscles secrete HFE2, a protein that promotes blood vessel integrity in healthy animals and in an animal model for multiple sclerosis.

Xue Fan Wang
Robin Vigouroux
Philippe P. Monnier
ResearchOpen Access03 Feb 2024
Nature Communications

Volume: 15, P: 1-16
Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products

Tracey Chapman
Lindsay F. Liddle
Linda Partridge
Research19 Jan 1995
Nature

Volume: 373, P: 241-244
Competitive Adsorption of Phosphate with Polygalacturonate and other Organic Anions on Kaolinite and Oxide Surfaces

S. NAGARAJAH
A. M. POSNER
J. P. QUIRK
Research03 Oct 1970
Nature

Volume: 228, P: 83-85
Drug resistance in papillary RCC: from putative mechanisms to clinical practicalities

The molecular mechanisms involved in papillary renal cell carcinoma (pRCC) development and drug resistance are diverse. In this Review, the authors summarize the current understanding of the mechanisms of resistance to currently used therapies in pRCC and make recommendations for future preclinical and clinical studies.

Anna Brodziak
Paweł Sobczuk
Anna M. Czarnecka
Reviews10 Oct 2019
Nature Reviews Urology

Volume: 16, P: 655-673
Attenuation of Mengo virus through genetic engineering of the 5′ noncoding poly(C) tract

Gregory M. Duke
Jorge E. Osorio
Ann C. Palmenberg
Research01 Feb 1990
Nature

Volume: 343, P: 474-476
Metallic glasses as novel catalysts

W. E. Brower Jr
M. S. Matyjaszczyk
G. V. Smith
Research10 Feb 1983
Nature

Volume: 301, P: 497-499
Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

Rosel M. Mulkey
Shogo Endo
Robert C. Malenka
Research09 Jun 1994
Nature

Volume: 369, P: 486-488
Expression of Bcl-2 family of proteins in fresh myeloma cells

N Harada
H Hata
H Mitsuya
Research22 Oct 1998
Leukemia

Volume: 12, P: 1817-1820
Molecular and immunological dissection of diffuse large B cell lymphoma: CD5⁺, and CD5⁻ with CD10⁺ groups may constitute clinically relevant subtypes

S Harada
R Suzuki
M Seto
Research09 Sept 1999
Leukemia

Volume: 13, P: 1441-1447
PDGFRα demarcates the cardiogenic clonogenic Sca1⁺ stem/progenitor cell in adult murine myocardium

Adult cardiac progenitor/stem cells (CPSCs) possess valuable potential for heart repair that is limited by the elusiveness of these cells. Here Noseda et al. refine the definition of murine CPSCs producing stem cell antigen 1 (Sca1), mapping the cardiogenic signature and clonogenicity to the subgroup of Sca1⁺cells expressing PDGFRα.

Michela Noseda
Mutsuo Harada
Michael D. Schneider
ResearchOpen Access18 May 2015
Nature Communications

Volume: 6, P: 1-16
On the reported optical activity of amino acids in the Murchison meteorite

Jeffrey L. Bada
John R. Cronin
Spencer Steinberg
Research10 Feb 1983
Nature

Volume: 301, P: 494-496

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