Nature Search

Chronically implantable μLED arrays for optogenetic cortical surface stimulation in mice

Achieving high resolution with optical neural interfaces is challenging. Here, the authors developed and chronically implanted 100-pixel microLED arrays on the surface of the mouse auditory cortex for optogenetic behavioural experiements.

Ryan Greer
Antonin Verdier
Keith Mathieson
ResearchOpen Access14 Jan 2026
Nature Communications

Volume: 17, P: 1-17
A new deep-sea crustacean family of Tanaidacea is established from Aotearoa New Zealand and Southeast Australia based principally on morphology

Graham J. Bird
Magdalena Błażewicz
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-60
Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus

Jing Gao
Clémence Abriat
France Daigle
ResearchOpen Access11 Feb 2026
Scientific Reports

Volume: 16, P: 1-13
Integrative systematics and ecology of a new deep-sea family of tanaidacean crustaceans

Magdalena Błażewicz
Piotr Jóźwiak
Inmaculada Frutos
ResearchOpen Access10 Dec 2019
Scientific Reports

Volume: 9, P: 1-70
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Macrophages are critical in limiting replication of herpes simplex virus type 1 (HSV-1). Here the authors show how acid ceramidase and its enzymatic product sphingosine enable multivesicular bodies to function as an anti-viral mechanism.

Judith Lang
Patrick Bohn
Karl S. Lang
ResearchOpen Access12 Mar 2020
Nature Communications

Volume: 11, P: 1-15
Joint neutrino oscillation analysis from the T2K and NOvA experiments

The joint analysis of datasets from NOvA and T2K, the two currently operating long-baseline neutrino oscillation experiments, provides new constraints related to neutrino masses and fundamental symmetries.

S. Abubakar
M. A. Acero
S. Zsoldos
ResearchOpen Access22 Oct 2025
Nature

Volume: 646, P: 818-824
The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process

Translation of evidence about dementia risk into effective public health policy is a challenge. In this Consensus Statement, Demnitz-King and colleagues present 56 policy recommendations for dementia prevention, providing policymakers with a foundation for designing and implementing evidence-based dementia prevention strategies, prioritizing clear communication, targeted intervention and sustained research investment.

Harriet Demnitz-King
Sube Banerjee
Iain Lang
Reviews16 Jan 2026
Nature Reviews Neurology

Volume: 22, P: 123-135
Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids

The authors develop an EM-based method to directly visualize R-loops. Applying this method to transcription-replication conflicts in human and bacterial cells, they show that DNA:RNA hybrids accumulate primarily behind replication forks, and are linked to fork slowing and fork reversal.

Henriette Stoy
Katharina Zwicky
Massimo Lopes
ResearchOpen Access02 Mar 2023
Nature Structural & Molecular Biology

Volume: 30, P: 348-359
T-bet⁺ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms

Endogenous retroviruses (ERV) can induce immune responses and the control of these viruses uses immune mechanisms also involved in autoimmunity. Here, the authors characterize the control of ERVs in mice and show age-associated B cell control and nucleic acid sensing TLR pathway involvement.

Eileen Rauch
Timm Amendt
Philipp Yu
ResearchOpen Access09 Feb 2024
Nature Communications

Volume: 15, P: 1-19
Randomized phase 3 trial of Ropeginterferon alfa-2b versus surveillance after tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia (ENDURE/CML-IX)

Andreas Burchert
Franck E. Nicolini
Christian Michel
ResearchOpen Access12 Jan 2026
Leukemia

Volume: 40, P: 410-417
Temporal BMP4 effects on mouse embryonic and extraembryonic development

Temporally dynamic extraembryonic and embryonic BMP4 signalling shapes mouse embryo lineage choices.

Ron Hadas
Hernan Rubinstein
Yonatan Stelzer
ResearchOpen Access18 Sept 2024
Nature

Volume: 634, P: 652-661
Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Pulmonary carcinoids account for about 2% of pulmonary neoplasms. Here, the authors carry out gene copy number analysis, genome/exome, and transcriptome sequencing of pulmonary carcinoids and identify frequent mutations in chromatin-remodelling genes that can drive tumorigenesis in these tumours.

Lynnette Fernandez-Cuesta
Martin Peifer
Roman K. Thomas
Research27 Mar 2014
Nature Communications

Volume: 5, P: 1-7
Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

Krebs and colleagues identify multiple mAbs that recognize either the RBD or the NTD of SARS-CoV-2 spike protein that have potent cross-neutralizing activities against variants of concern. Combinatorial mAb cocktails have complementary effects on viral neutralization and Fc effector functions and can protect against SARS-CoV-2 escape mutants.

Vincent Dussupt
Rajeshwer S. Sankhala
Shelly J. Krebs
ResearchOpen Access29 Oct 2021
Nature Immunology

Volume: 22, P: 1503-1514
Diversity under a magnifier lens: the case of Typhlotanaidae (Crustacea: Tanaidacea) in the N Atlantic

Marta Gellert
Magdalena Błażewicz
Graham J. Bird
ResearchOpen Access05 Jul 2023
Scientific Reports

Volume: 13, P: 1-86
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Comprehensive genomic profiles of small cell lung cancer

Genomic sequencing of 110 human small cell lung cancers identifies genomic signatures including nearly ubiquitous bi-allelic inactivation of TP53 and RB1, a role for NOTCH family genes, and somatic rearrangements that create an oncogenic version of TP73.

Julie George
Jing Shan Lim
Roman K. Thomas
Research13 Jul 2015
Nature

Volume: 524, P: 47-53
Perceived realism of haptic rendering methods for bimanual high force tasks: original and replication study

Mario Lorenz
Andrea Hoffmann
Angelika C. Bullinger
ResearchOpen Access11 Jul 2023
Scientific Reports

Volume: 13, P: 1-17
Endocrine disruptors in the etiology of type 2 diabetes mellitus

Type 2 diabetes mellitus is one of the fastest growing public health problems. Both genetic background and environmental factors are responsible of its etiology. This Review discusses evidence of the relationship between adult and fetal exposure to common environmental endocrine disruptors and an increased risk of development of type 2 diabetes mellitus and other diseases related to insulin resistance.

Paloma Alonso-Magdalena
Ivan Quesada
Angel Nadal
Reviews05 Apr 2011
Nature Reviews Endocrinology

Volume: 7, P: 346-353
Understanding the ZIF-L to ZIF-8 transformation from fundamentals to fully costed kilogram-scale production

The metal-organic framework ZIF-8 has demonstrated promise for a wide range of applications, but its synthesis typically involves methodologies that are difficult or expensive to scale up. Here the authors show how the production of nano-ZIF-8 can be conducted at the 1kg scale in an economical manner through the intermediate phase ZIF-L.

Adam Deacon
Ludovic Briquet
Timothy Johnson
ResearchOpen Access09 Feb 2022
Communications Chemistry

Volume: 5, P: 1-10
Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

The molecular nature of large-cell neuroendocrine lung carcinomas (LCNEC) has remained unclear. Here, the authors show LCNECs represent a distinct transcriptional subgroup among lung cancers and comprise two molecular subgroups, type I (TP53 and STK11/KEAP1 alterations) and type II (TP53 and RB1 inactivation).

Julie George
Vonn Walter
Roman K. Thomas
ResearchOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1-13
The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

A pyrrolidine-based small-molecule inhibitor competes with H3K27me3 for binding to EED leading to inactivation of PRC2 and global reduction in H3K27me3 levels.

Yupeng He
Sujatha Selvaraju
William N Pappano
Research30 Jan 2017
Nature Chemical Biology

Volume: 13, P: 389-395
BRAF^V600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis

Tommaso Sconocchia
Johannes Foßelteder
Andreas Reinisch
ResearchOpen Access06 Sept 2023
Leukemia

Volume: 37, P: 2292-2296
The HLA-DQβ1 insertion is a strong achalasia risk factor and displays a geospatial north–south gradient among Europeans

Jessica Becker
Stephan L Haas
Johannes Schumacher
Research06 Jan 2016
European Journal of Human Genetics

Volume: 24, P: 1228-1231
Severe COVID-19 associated hyperglycemia is caused by beta cell dysfunction: a prospective cohort study

Jan Gojda
Kateřina Koudelková
Sabrina Schlesinger
ResearchOpen Access17 Jul 2023
Nutrition & Diabetes

Volume: 13, P: 1-11
The thiosemicarbazone Me₂NNMe₂ induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Sonja Hager
Katharina Korbula
Petra Heffeter
ResearchOpen Access15 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-17
Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Regina Weinmüllner
Barbara Zbiral
Johannes Grillari
ResearchOpen Access06 Mar 2020
npj Aging and Mechanisms of Disease

Volume: 6, P: 1-7

Search

Chronically implantable μLED arrays for optogenetic cortical surface stimulation in mice

A new deep-sea crustacean family of Tanaidacea is established from Aotearoa New Zealand and Southeast Australia based principally on morphology

Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus

Integrative systematics and ecology of a new deep-sea family of tanaidacean crustaceans

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

Joint neutrino oscillation analysis from the T2K and NOvA experiments

The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process

Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids

T-bet⁺ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms

Randomized phase 3 trial of Ropeginterferon alfa-2b versus surveillance after tyrosine kinase inhibitor discontinuation in chronic myeloid leukemia (ENDURE/CML-IX)

Temporal BMP4 effects on mouse embryonic and extraembryonic development

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

Diversity under a magnifier lens: the case of Typhlotanaidae (Crustacea: Tanaidacea) in the N Atlantic

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Comprehensive genomic profiles of small cell lung cancer

Perceived realism of haptic rendering methods for bimanual high force tasks: original and replication study

Endocrine disruptors in the etiology of type 2 diabetes mellitus

Understanding the ZIF-L to ZIF-8 transformation from fundamentals to fully costed kilogram-scale production

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

BRAF^V600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis

The HLA-DQβ1 insertion is a strong achalasia risk factor and displays a geospatial north–south gradient among Europeans

Severe COVID-19 associated hyperglycemia is caused by beta cell dysfunction: a prospective cohort study

The thiosemicarbazone Me₂NNMe₂ induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

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