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Advanced filters: Author: Malene Hall Jensen Clear advanced filters

  • The astrocytic transporter, GAT3, is a drug target for epilepsy. Here, the authors report the structures of human GAT3, bound to an inhibitor, to substrate GABA, or in substrate-free state, revealing the mechanism of transport and selective inhibition.

    • Jonas Sigurd Mortensen
    • Francesco Bavo
    • Azadeh Shahsavar
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-13