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Showing 1–4 of 4 results

Advanced filters: Author: Manuela Wende Clear advanced filters

Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification

BRCA1 and BRCA2 are well known breast cancer predisposition genes, however, many variants have not yet been classified for their pathogenicity. Here, the authors analyse a large combined cohort to provide evidence of variant pathogenicity.

Maria Zanti
Denise G. O’Mahony
Kyriaki Michailidou
ResearchOpen Access25 May 2025
Nature Communications

Volume: 16, P: 1-18
Neuron–astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain

Astrocytic glycogen dynamics is necessary to support neuronal transmission of long-term inflammatory pain signals in the spinal cord.

Sebastián Marty-Lombardi
Shiying Lu
Jan Siemens
ResearchOpen Access05 Mar 2024
Nature Metabolism

Volume: 6, P: 494-513
Publisher Correction: Synergistic effect of plasma-activated medium and novel indirubin derivatives on human skin cancer cells by activation of the AhR pathway

Henrike Rebl
Marie Sawade
Barbara Nebe
Amendments and CorrectionsOpen Access14 Mar 2022
Scientific Reports

Volume: 12, P: 1
Synergistic effect of plasma-activated medium and novel indirubin derivatives on human skin cancer cells by activation of the AhR pathway

Henrike Rebl
Marie Sawade
Barbara Nebe
ResearchOpen Access15 Feb 2022
Scientific Reports

Volume: 12, P: 1-15