While progress has been made in treating advanced non-small-cell lung cancer, patients would further benefit from methods that detect progressive premalignant lesions and strategies that effectively intercept progression. In this Review, Mazzilli et al. explore recent advances in identifying premalignant lesions, highlighting their disease aetiology and devising approaches for stratification and interventions aimed at halting the progression to cancer.
- Sarah A. Mazzilli
- Zahraa Rahal
- Avrum E. Spira
