Nature Search

Observation of universal dynamics in a spinor Bose gas far from equilibrium

The emergence of universal dynamics far from equilibrium is observed by evaluating spatially resolved spin correlations in a quasi-one-dimensional spinor Bose–Einstein condensate.

Maximilian Prüfer
Philipp Kunkel
Markus K. Oberthaler
Research07 Nov 2018
Nature

Volume: 563, P: 217-220
Dihydroquinazolinones as adaptative C(sp³) handles in arylations and alkylations via dual catalytic C–C bond-functionalization

Although derived from feedstock chemicals and therefore in principle abundant, ketones are not widely used as cross-coupling partners in organic synthesis. Herein, the authors use ketone derivatives as one-electron handles for forging C(sp3) architectures via dual photo- and nickel catalysis.

Xin-Yang Lv
Roman Abrams
Ruben Martin
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-8
Transition from a polaronic condensate to a degenerate Fermi gas of heteronuclear molecules

Tuning interspecies interactions in atomic Bose–Fermi mixtures is shown to drive the system through a quantum phase transition. This enables the generation of heteronuclear molecules in the quantum-degenerate regime.

Marcel Duda
Xing-Yan Chen
Xin-Yu Luo
ResearchOpen Access13 Feb 2023
Nature Physics

Volume: 19, P: 720-725
PGRL2 triggers degradation of PGR5 in the absence of PGRL1

It is currently thought that the thylakoid proteins PGRL1 and PGR5 form a complex to mediate cyclic electron flow (CEF) around photosystem I. Here the authors show that CEF can in fact be mediated by PGR5 alone and that PGRL1 and the homologous PGRL2 modify the process by modulating PGR5 activity and stability.

Thilo Rühle
Marcel Dann
Dario Leister
ResearchOpen Access24 Jun 2021
Nature Communications

Volume: 12, P: 1-14
smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

Marcel van den Heuvel
Philip W. Ingham
Research08 Aug 1996
Nature

Volume: 382, P: 547-551
NMDA-dependent superoxide production and neurotoxicity

Mireille Lafon-Cazal
Sylvia Pietri
Joel Bockaert
Research05 Aug 1993
Nature

Volume: 364, P: 535-537
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

High levels of neutralizing antibodies are successfully elicited against SARS-CoV-2 variants of concern, including omicron, after three exposures to the viral spike protein, mediated by vaccination with BNT162b2 alone or by a combination of vaccination and infection.

Paul R. Wratil
Marcel Stern
Ulrike Protzer
Research28 Jan 2022
Nature Medicine

Volume: 28, P: 496-503
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma

Keppler and colleagues show that individuals with hematological cancers rapidly develop potent infection-neutralizing antibodies and a robust T cell response against several SARS-CoV-2 variants of concern in response to mRNA vaccination.

Andrea Keppler-Hafkemeyer
Christine Greil
Oliver T. Keppler
ResearchOpen Access21 Dec 2022
Nature Cancer

Volume: 4, P: 81-95
Elastocaloric, barocaloric and magnetocaloric effects in spin crossover polymer composite films

Spin-crossover materials are promising for caloric cooling, but their powder nature prevents exploring elastocaloric properties. Here, the authors propose spin-crossover polymer composites with giant elastocaloric effects.

Klara Lünser
Eyüp Kavak
Lluís Mañosa
ResearchOpen Access22 Jul 2024
Nature Communications

Volume: 15, P: 1-10
Direct-bandgap emission from hexagonal Ge and SiGe alloys

A hexagonal (rather than cubic) alloy of silicon and germanium that has a direct (rather than indirect) bandgap emits light efficiently across a range of wavelengths, enabling electronic and optoelectronic functionalities to be combined on a single chip.

Elham M. T. Fadaly
Alain Dijkstra
Erik P. A. M. Bakkers
Research08 Apr 2020
Nature

Volume: 580, P: 205-209
Adrenal tropism of SARS-CoV-2 and adrenal findings in a post-mortem case series of patients with severe fatal COVID-19

Progressive respiratory failure is the primary cause of death in patients with COVID-19, but pathologies in other tissues may also occur. Here the authors report that adrenal tropism of SARS-CoV-2 is associated with adrenalitis, reduced adrenal cortisol levels and severe adrenal damage in a post-mortem case series of patients with severe fatal COVID-19.

Tanja Paul
Stephan Ledderose
Martina Rudelius
ResearchOpen Access24 Mar 2022
Nature Communications

Volume: 13, P: 1-12
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells

FCH domain only 1 (FCHO1) is a key molecule involved in clathrin-mediated endocytosis (CME). Here, the authors report homozygous FCHO1 mutations in individuals with variable T and B cell lymphopenia, which are associated with loss-of-function of FCHO1 and impaired formation of clathrin-coated pits in T cells.

Marcin Łyszkiewicz
Natalia Ziętara
Christoph Klein
ResearchOpen Access25 Feb 2020
Nature Communications

Volume: 11, P: 1-15
Scientific assessments to facilitate deliberative policy learning

Martin Kowarsch
Jennifer Garard
Ottmar Edenhofer
ResearchOpen Access13 Dec 2016
Palgrave Communications

Volume: 2, P: 1-20
Sunda arc mantle source δ¹⁸O value revealed by intracrystal isotope analysis

Subduction zone volcanoes are underlain by extensive magma plumbing systems, which can obscure original mantle source signals. Here, the authors show that intra-crystal oxygen isotope analysis of clinopyroxenes from the Sunda arc (Indonesia) reveal the δ18 O value of the sub-arc mantle.

Frances M. Deegan
Martin J. Whitehouse
Osvaldo González-Maurel
ResearchOpen Access24 Jun 2021
Nature Communications

Volume: 12, P: 1-10
Microenvironments on individual sand grains enhance nitrogen loss in coastal sediments

Farooq Moin Jalaluddin
Soeren Ahmerkamp
Marcel M. M. Kuypers
ResearchOpen Access11 May 2025
Scientific Reports

Volume: 15, P: 1-14
Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

The signalling cascade involved in lung ischaemia–reperfusion-induced oedema is poorly understood. Using knockout mice, Weissmannet al. propose a model in which reactive oxygen species production by endothelial NOX2 leads to phospholipase C-γ activation, DAG kinase inhibition and subsequent TRPC6 activation.

Norbert Weissmann
Akylbek Sydykov
Alexander Dietrich
ResearchOpen Access31 Jan 2012
Nature Communications

Volume: 3, P: 1-10
Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA

The HECT-like E3 ligase SopA inSalmonellahas been suggested to activate host RING ligases TRIM56 and TRIM65. Here, the authors use mass spectrometry, crystal structures and biochemistry to examine the interactions between these proteins in detail.

Evgenij Fiskin
Sagar Bhogaraju
Ivan Dikic
ResearchOpen Access13 Jan 2017
Nature Communications

Volume: 8, P: 1-14
FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

In this study the authors identify a possible link between the gene FAM222A and brain atrophy. The protein it encodes is found to accumulate in plaques seen in Alzheimer’s disease, and functional analysis suggests it interacts with amyloid-beta.

Tingxiang Yan
Jingjing Liang
Xinglong Wang
ResearchOpen Access21 Jan 2020
Nature Communications

Volume: 11, P: 1-16
14-3-3σ controls mitotic translation to facilitate cytokinesis

A function for 14-3-3σ in regulating the translation of proteins in mitosis is defined. During mitosis, translation normally switches from a 'cap-dependent' to 'cap-independent' mechanism, but cells lacking 14-3-3σ don't make this switch and consequently have difficulties in cell division.

Erik W. Wilker
Marcel A. T. M. van Vugt
Michael B. Yaffe
Research15 Mar 2007
Nature

Volume: 446, P: 329-332
Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical diagnosis to show that tissue volume changes appear earlier in the basal forebrain than in the entorhinal cortex.

Taylor W. Schmitz
R. Nathan Spreng
Ansgar J. Furst
ResearchOpen Access04 Nov 2016
Nature Communications

Volume: 7, P: 1-13
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Late-onset Alzheimer's disease (LOAD) is a complex multi-factorial disorder. Here, the authors perform a data-driven analysis of LOAD progression, including multimodal brain imaging, plasma and CSF biomarkers, and find vascular dysfunction is among the earliest and strongest altered events.

Y. Iturria-Medina
R. C. Sotero
Ansgar J. Furst
ResearchOpen Access21 Jun 2016
Nature Communications

Volume: 7, P: 1-14
Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE

Brain-iron elevation is implicated in Alzheimer’s disease (AD), but the impact of the metal on disease outcomes has not been analysed in a longitudinal study. Here, the authors examine the association between the levels of ferritin, an iron storage protein, in the cerebrospinal fluid (CSF) of AD patients and show that CSF ferritin levels predict AD outcomes.

Scott Ayton
Noel G. Faux
Ansgar J. Furst
ResearchOpen Access19 May 2015
Nature Communications

Volume: 6, P: 1-9
Author Correction: Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells

Marcin Łyszkiewicz
Natalia Ziętara
Christoph Klein
Amendments and CorrectionsOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Progressive diseases tend to be heterogeneous in their underlying aetiology mechanism, disease manifestation, and disease time course. Here, Young and colleagues devise a computational method to account for both phenotypic heterogeneity and temporal heterogeneity, and demonstrate it using two neurodegenerative disease cohorts.

Alexandra L Young
Razvan V Marinescu
Ansgar J Furst
ResearchOpen Access15 Oct 2018
Nature Communications

Volume: 9, P: 1-16
Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Elodie Piot
Félix Renard
Maria Luisa Mandelli
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Prognosis and quality of life in patients with locally advanced rectal cancer after abdominoperineal resection in the CAO/ARO/AIO-04 randomized phase 3 trial

Jochen Gaedcke
Malte Sahrhage
H. Leber
ResearchOpen Access13 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
Pushing the mass limit for intact launch and photoionization of large neutral biopolymers

Generating and detecting neutral biomolecular beams is an important analytical challenge, particularly for high-mass peptides. Here, femtosecond laser desorption is shown to enable the intact volatilization of complex polypeptides that can still be photoionized at masses beyond 20 kDa, because they are tryptophan-rich.

Jonas Schätti
Philipp Rieser
Markus Arndt
ResearchOpen Access10 Dec 2018
Communications Chemistry

Volume: 1, P: 1-8
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity

Daniel Stern
Tanja C. Meyer
Brigitte G. Dorner
ResearchOpen Access09 Dec 2023
Scientific Reports

Volume: 13, P: 1-22
Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

Tingxiang Yan
Jingjing Liang
Xinglong Wang
Amendments and CorrectionsOpen Access11 Jul 2022
Nature Communications

Volume: 13, P: 1-2
AMPK-independent inhibition of human macrophage ER stress response by AICAR

Marcel Boß
Yvette Newbatt
Dmitry Namgaladze
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes

Timothy Warwick
Marcel H. Schulz
Sabine Seuter
ResearchOpen Access22 Mar 2021
Scientific Reports

Volume: 11, P: 1-16
The trend of disruption in the functional brain network topology of Alzheimer’s disease

Alireza Fathian
Yousef Jamali
Ansgar J. Furst
ResearchOpen Access02 Sept 2022
Scientific Reports

Volume: 12, P: 1-17
Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization

Yeonwoo Chung
Hyunju Lee
Kristin Fargher
ResearchOpen Access27 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Kilian Hett
Vinh-Thong Ta
Kristin Fargher
ResearchOpen Access25 Sept 2019
Scientific Reports

Volume: 9, P: 1-16
Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Garam Lee
Kwangsik Nho
Kristin Fargher
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-12
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

Suprateek Kundu
Joshua Lukemire
Ansgar J. Furst
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-18
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

Margherita Squillario
Giulia Abate
Kristin Fargher
ResearchOpen Access21 Jul 2020
Scientific Reports

Volume: 10, P: 1-12
Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

Yogatheesan Varatharajah
Vijay K. Ramanan
Kristin Fargher
ResearchOpen Access19 Feb 2019
Scientific Reports

Volume: 9, P: 1-15
Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

Xinpeng Shen
Sisi Ma
Kristin Fargher
ResearchOpen Access19 Feb 2020
Scientific Reports

Volume: 10, P: 1-12
Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Lei Du
Kefei Liu
Kristin Fargher
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-14
A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer’s disease

Haochen Liu
Xiaoting Zhou
Kristin Fargher
ResearchOpen Access07 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Author Correction: Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Garam Lee
Kwangsik Nho
Kristin Fargher
Amendments and CorrectionsOpen Access01 Aug 2023
Scientific Reports

Volume: 13, P: 1
Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification

Kilian Hett
Vinh-Thong Ta
Kristin Fargher
Amendments and CorrectionsOpen Access30 Jun 2020
Scientific Reports

Volume: 10, P: 1

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