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Showing 1–4 of 4 results
Advanced filters: Author: Marcello Moccia Clear advanced filters

  • The 2024 revision of the McDonald criteria for diagnosis of multiple sclerosis marks a substantial departure from previous iterations, establishing a unified framework that integrates presentation, lesion topography and a flexible combination of paraclinical tools. This Clinical Outlook considers the major changes and their clinical implementation, and the implications of the new criteria.

    • Marcello Moccia
    • Olga Ciccarelli
    • Alan Thompson
    Comments & Opinion
    Nature Reviews Neurology
    Volume: 21, P: 664-666

  • In clinical trials, outcome measures might determine whether a drug is worthy of further development; in the clinic, they might guide important treatment decisions. Here, Tur and colleagues help clinicians and researchers navigate the maze of options for clinical, neuroimaging, patient-reported and composite outcome measures in multiple sclerosis.

    • Carmen Tur
    • Marcello Moccia
    • Olga Ciccarelli
    Reviews
    Nature Reviews Neurology
    Volume: 14, P: 75-93

  • Approximately half of the people currently with multiple sclerosis (MS) are ≥50 years of age, yet guidelines for management of MS in older age are lacking. This Consensus statement presents the outcomes of an International Advisory Committee on Clinical Trials (IACCT) in MS workshop on ageing and MS, including recommendations for advancing research, care and awareness.

    • Anneke van der Walt
    • Eva M. M. Strijbis
    • Yinan Zhang
    Reviews
    Nature Reviews Neurology
    Volume: 21, P: 432-448