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Showing 1–5 of 5 results
Advanced filters: Author: Marco Antonio Pretti Clear advanced filters

  • Visceral adiposity is a risk factor for severe COVID-19, and infection of adipose tissue by SARS-CoV-2 has been reported. Here the authors confirm that human adipose tissue is a possible site for SARS-CoV-2 infection, but the degree of adipose tissue infection and the way adipocytes respond to the virus depend on the adipose tissue depot and the viral strain.

    • Tatiana Dandolini Saccon
    • Felippe Mousovich-Neto
    • Marcelo A. Mori
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Tumour-associated myeloid cells have been linked to patient outcome and treatment response in multiple cancer types. Here, the authors use deconvolution of single cell RNA-sequencing data to identify myeloid populations which are prognostic across cancer types.

    • Gabriela Rapozo Guimarães
    • Giovanna Resk Maklouf
    • Mariana Boroni
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-23

  • The biological understanding of poor prognosis associated with lymph node metastasis in head and neck cancer (HNC) remains crucial. Here, a proteomic characterisation of 140 multisite samples from a 59-HNC patient cohort and machine learning reveals potential biomarkers and metastasis related signatures.

    • Ariane F. Busso-Lopes
    • Leandro X. Neves
    • Adriana F. Paes Leme
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-24

  • The Cancer Genome Atlas Research Network report integrated genomic and molecular analyses of 164 squamous cell carcinomas and adenocarcinomas of the oesophagus; they find genomic and molecular features that differentiate squamous and adenocarcinomas of the oesophagus, and strong similarities between oesophageal adenocarcinomas and the chromosomally unstable variant of gastric adenocarcinoma, suggesting that gastroesophageal adenocarcinoma is a single disease entity.

    • Jihun Kim
    • Reanne Bowlby
    • Jiashan Zhang
    ResearchOpen Access
    Nature
    Volume: 541, P: 169-175