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Nature Cancer (1)

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Advanced filters: Author: Mariëtte E. G. Kranendonk Clear advanced filters

De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function

Bessler et al. developed a human organoid model for H3.3K27M-altered diffuse midline glioma that recapitulates key tumor features and demonstrated its utility for modeling CAR T cell and microglia functions.

Nils Bessler
Amber K. L. Wezenaar
Anne C. Rios
ResearchOpen Access05 Jan 2026
Nature Cancer

Volume: 7, P: 316-333

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De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function

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