The centromere of a chromosome contains regions of heterochromatin that have diverse roles during chromosome segregation. This paper demonstrates that during mitosis in fission yeast, the main function for centromeric heterochromatin is to recruit cohesin. In contrast, during meiosis, the most important function for heterochromatin is to recruit the cohesin protector shugoshin to centromeres. This function is conserved in human cells.
- Yuya Yamagishi
- Takeshi Sakuno
- Yoshinori Watanabe
